Product Information

CARBIDOPA-LEVODOPA 25-100 TAB is a generic product labeled by Advagen Pharma Ltd., priced at $0.0766 per EA under NDC 72888010705. Its NADAC has been published 177 times since Apr 5, 2023.

FDA first approved this application on Sep 21, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CARBIDOPA-LEVODOPA 25-100 TAB

carbidopa and levodopa
$0.0766per EA

Strength

25; 100 mg/1; mg/1

NDC

72888010705

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

CARBIDOPA; LEVODOPA

Approval Type

Generic (ANDA)

FDA Application

ANDA216505

FDA Approved

9/21/2022

TE Code

AB

On Market Since

9/21/2022

Pharmacological Classes

Amino Acids
Aromatic
Aromatic Amino Acid

Price Statistics

The NADAC for CARBIDOPA-LEVODOPA 25-100 TAB has been published 177 times since Apr 5, 2023, and over the history we have for it it has declined 29.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0766 per EA
All-time high$0.1093 (Apr 12, 2023)
All-time low$0.0617 (Nov 20, 2024)
52-week high$0.0876
52-week low$0.0719
Median price$0.0891
Average price$0.0863
Largest weekly change-30.7% (Nov 20, 2024)
Weeks tracked177
Tracking sinceApr 5, 2023

Price History

1W

+1.4%

1M

+1.4%

3M

+6.6%

6M

+1.2%

1Y

-12.6%

3Y

-19.6%

5Y

N/A

All

-29.9%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 6% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CARBIDOPA-LEVODOPA 25-100 TAB?

The current National Average Drug Acquisition Cost (NADAC) for CARBIDOPA-LEVODOPA 25-100 TAB, manufactured by Advagen Pharma Ltd., is $0.0766 per EA (NDC 72888010705), effective Aug 19, 2026.

How has the price of CARBIDOPA-LEVODOPA 25-100 TAB changed over time?

Over the history we have for it, the NADAC for CARBIDOPA-LEVODOPA 25-100 TAB has declined 29.9%. It has been tracked across 177 weekly CMS publications since Apr 5, 2023.

What are the highest and lowest recorded NADAC prices for CARBIDOPA-LEVODOPA 25-100 TAB?

Since Apr 5, 2023, the NADAC for CARBIDOPA-LEVODOPA 25-100 TAB has ranged from a low of $0.0617 (Nov 20, 2024) to a high of $0.1093 (Apr 12, 2023), with a median of $0.0891 per EA.

Are there cheaper alternatives to CARBIDOPA-LEVODOPA 25-100 TAB?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CARBIDOPA-LEVODOPA 25-100 TAB, is $0.0724 per EA — about 6% below CARBIDOPA-LEVODOPA 25-100 TAB.

Who manufactures CARBIDOPA-LEVODOPA 25-100 TAB?

CARBIDOPA-LEVODOPA 25-100 TAB (NDC 72888010705) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.