Product Information
SINEMET 25-100 MG TABLET is a brand product labeled by Organon LLC, priced at $1.4236 per EA under NDC 78206019001. Its NADAC has been published 60 times since May 7, 2025.
The High Outlier badge above means this manufacturer's average price in the carbidopa and levodopa market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
25; 100 mg/1; mg/1
Manufacturer
Organon LLCNDC
78206019001
Classification
Brand
Dosage Form
TABLET
Route
ORAL
Last Updated
1/1/2026
Active Ingredients
CARBIDOPA; LEVODOPAApproval Type
New Drug (NDA)
FDA Application
NDA017555On Market Since
2/28/2025
Pharmacological Classes
Price Statistics
The NADAC for SINEMET 25-100 MG TABLET has been published 60 times since May 7, 2025, and over the history we have for it it has risen 5.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.4236 per EA |
|---|---|
| All-time high | $1.4236 (Jun 24, 2026) |
| All-time low | $1.3558 (Dec 17, 2025) |
| 52-week high | $1.4236 |
| 52-week low | $1.3558 |
| Median price | $1.3566 |
| Average price | $1.3843 |
| Largest weekly change | +5.0% (Jan 7, 2026) |
| Weeks tracked | 60 |
| Tracking since | May 7, 2025 |
Generic Alternatives
The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 95% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of SINEMET 25-100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SINEMET 25-100 MG TABLET, manufactured by Organon LLC, is $1.4236 per EA (NDC 78206019001), effective Jun 24, 2026.
How has the price of SINEMET 25-100 MG TABLET changed over time?
Over the history we have for it, the NADAC for SINEMET 25-100 MG TABLET has risen 5.0%. It has been tracked across 60 weekly CMS publications since May 7, 2025.
What are the highest and lowest recorded NADAC prices for SINEMET 25-100 MG TABLET?
Since May 7, 2025, the NADAC for SINEMET 25-100 MG TABLET has ranged from a low of $1.3558 (Dec 17, 2025) to a high of $1.4236 (Jun 24, 2026), with a median of $1.3566 per EA.
Are there cheaper alternatives to SINEMET 25-100 MG TABLET?
Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, CARBIDOPA-LEVODOPA 25-100 TAB, is $0.0724 per EA — about 95% below SINEMET 25-100 MG TABLET.
Who manufactures SINEMET 25-100 MG TABLET?
SINEMET 25-100 MG TABLET (NDC 78206019001) is labeled by Organon LLC, and CMS classifies it as a brand product.
Related Drugs
Same classification