Product Information
TRAMADOL HCL 25 MG TABLET is a generic product labeled by Advagen Pharma Ltd., priced at $3.3346 per EA under NDC 72888016230. Its NADAC has been published 110 times since Jul 17, 2024.
FDA first approved this application on Jun 28, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Advagen Pharma Ltd.NDC
72888016230
Classification
Generic
Dosage Form
TABLET, COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
TRAMADOL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA208708FDA Approved
6/28/2019
TE Code
AB
On Market Since
11/28/2023
Pharmacological Classes
Price Statistics
The NADAC for TRAMADOL HCL 25 MG TABLET has been published 110 times since Jul 17, 2024, and over the history we have for it it has risen 33.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.3346 per EA |
|---|---|
| All-time high | $3.3840 (Feb 11, 2026) |
| All-time low | $2.4916 (Jul 17, 2024) |
| 52-week high | $3.3840 |
| 52-week low | $3.1736 |
| Median price | $3.1435 |
| Average price | $3.0843 |
| Largest weekly change | +7.1% (Sep 18, 2024) |
| Weeks tracked | 110 |
| Tracking since | Jul 17, 2024 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Tramadol Hydrochloride market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRAMADOL HCL 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TRAMADOL HCL 25 MG TABLET, manufactured by Advagen Pharma Ltd., is $3.3346 per EA (NDC 72888016230), effective Aug 19, 2026.
How has the price of TRAMADOL HCL 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for TRAMADOL HCL 25 MG TABLET has risen 33.8%. It has been tracked across 110 weekly CMS publications since Jul 17, 2024.
What are the highest and lowest recorded NADAC prices for TRAMADOL HCL 25 MG TABLET?
Since Jul 17, 2024, the NADAC for TRAMADOL HCL 25 MG TABLET has ranged from a low of $2.4916 (Jul 17, 2024) to a high of $3.3840 (Feb 11, 2026), with a median of $3.1435 per EA.
Are there cheaper alternatives to TRAMADOL HCL 25 MG TABLET?
No other NADAC-published product currently shares the active ingredient and strength of TRAMADOL HCL 25 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures TRAMADOL HCL 25 MG TABLET?
TRAMADOL HCL 25 MG TABLET (NDC 72888016230) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.