Product Information

NAPROXEN DR 500 MG TABLET is a generic product labeled by TruPharma LLC, priced at $1.8643 per EA under NDC 52817038110. Its NADAC has been published 142 times since Dec 6, 2023.

FDA first approved this application on May 31, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Naproxen market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

NAPROXEN DR 500 MG TABLET

Naproxen
$1.8643per EA
High Outlier

Strength

500 mg/1

Manufacturer

TruPharma LLC

NDC

52817038110

Classification

Generic

Dosage Form

TABLET, DELAYED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

NAPROXEN

Approval Type

Generic (ANDA)

FDA Application

ANDA216908

FDA Approved

5/31/2023

TE Code

AB

On Market Since

7/27/2023

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for NAPROXEN DR 500 MG TABLET has been published 142 times since Dec 6, 2023, and over the history we have for it it has declined 43.9%. The table below summarizes its recorded NADAC range and movement.

Current price$1.8643 per EA
All-time high$3.6637 (Jan 10, 2024)
All-time low$1.5737 (Nov 20, 2024)
52-week high$2.1287
52-week low$1.7881
Median price$2.0206
Average price$2.1310
Largest weekly change-23.4% (Nov 20, 2024)
Weeks tracked142
Tracking sinceDec 6, 2023

Price History

1W

+0.2%

1M

+0.2%

3M

-2.2%

6M

+2.4%

1Y

-8.1%

3Y

N/A

5Y

N/A

All

-43.9%

Generic Alternatives

The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 97% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of NAPROXEN DR 500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN DR 500 MG TABLET, manufactured by TruPharma LLC, is $1.8643 per EA (NDC 52817038110), effective Aug 19, 2026.

How has the price of NAPROXEN DR 500 MG TABLET changed over time?

Over the history we have for it, the NADAC for NAPROXEN DR 500 MG TABLET has declined 43.9%. It has been tracked across 142 weekly CMS publications since Dec 6, 2023.

What are the highest and lowest recorded NADAC prices for NAPROXEN DR 500 MG TABLET?

Since Dec 6, 2023, the NADAC for NAPROXEN DR 500 MG TABLET has ranged from a low of $1.5737 (Nov 20, 2024) to a high of $3.6637 (Jan 10, 2024), with a median of $2.0206 per EA.

Are there cheaper alternatives to NAPROXEN DR 500 MG TABLET?

Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, NAPROXEN 500 MG TABLET, is $0.0580 per EA — about 97% below NAPROXEN DR 500 MG TABLET.

Who manufactures NAPROXEN DR 500 MG TABLET?

NAPROXEN DR 500 MG TABLET (NDC 52817038110) is labeled by TruPharma LLC, and CMS classifies it as a generic product.