Temozolomide

104 NDCs across 9 manufacturers|93 Generic,11 Brand

Temozolomide is used to treat glioblastoma and melanoma, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on Aug 11, 1999, and the first generic was approved Mar 1, 2010. FDA's Orange Book lists 58 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $39K on Temozolomide across 58 claims for 18 beneficiaries.

Temozolomide is available as 104 NDCs from 9 manufacturers (93 generic, 11 brand), with NADAC prices from $0.88 to $1091.67 per EA — the most expensive product costs about 1,241× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

104

93G / 11B

Manufacturers

competing in market

Price Spread

$0.88 – $1091.67

per EA

7d Activity

14↓90 flat

avg -8.1% WoW · of 104 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Explore this market from other angles

Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.

Top supplier

Sun Pharmaceutical Industries Inc. manufacturer profile

Open the supplier page for the manufacturer with the strongest footprint in this market.

Lead class

Alkylating Drug class view

See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.

Trend hub

Latest market trends

Move from this single molecule into the current cross-market mover and volatility view.

Guide

How to interpret NADAC

Review the benchmark methodology behind the prices and spreads shown on this market page.

Manufacturer Breakdown

9 manufacturers producing TEMOZOLOMIDE(2 pricing outliers)

Sun Pharmaceutical Industries Inc.

Merck Sharp & Dohme LLC

Accord Healthcare Inc.

11 NDCs

$9.1504

avg/unit

Rising Pharma Holdings Inc.

11 NDCs

$9.1504

avg/unit

Camber Pharmaceuticals Inc.

Amneal Pharmaceuticals LLC

11 NDCs

$9.1504

avg/unit

Ascend Laboratories, LLC

11 NDCs

$9.1504

avg/unit

Nivagen Pharmaceuticals Inc.

6 NDCs

$11.2768

avg/unit

Drug Portfolio

104 NDCs total, 104 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
TEMODAR 250 MG CAPSULE	00085141702	Merck Sharp & Dohme LLC	$1091.6709 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 180 MG CAPSULE	00085143003	Merck Sharp & Dohme LLC	$634.6595 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 180 MG CAPSULE	00085143004	Merck Sharp & Dohme LLC	$634.6595 per EA	High Outlier	Brand	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	47335093021	Sun Pharmaceutical Industries Inc.	$313.4079 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	47335093080	Sun Pharmaceutical Industries Inc.	$313.4079 per EA	High Outlier	Generic	—	Alkylating Drug
TEMODAR 140 MG CAPSULE	00085142504	Merck Sharp & Dohme LLC	$306.9869 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 140 MG CAPSULE	00085142503	Merck Sharp & Dohme LLC	$306.9869 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 100 MG CAPSULE	00085136604	Merck Sharp & Dohme LLC	$216.4714 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 100 MG CAPSULE	00085136603	Merck Sharp & Dohme LLC	$216.4714 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 20 MG CAPSULE	00085151903	Merck Sharp & Dohme LLC	$89.9177 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 20 MG CAPSULE	00085151904	Merck Sharp & Dohme LLC	$89.9177 per EA	High Outlier	Brand	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	16729013053	Accord Healthcare Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	16571082041	Rising Pharma Holdings Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	75834014514	Nivagen Pharmaceuticals Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	31722041514	Camber Pharmaceuticals Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	16729013054	Accord Healthcare Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	31722041531	Camber Pharmaceuticals Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	73043001514	Devatis Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	65162080551	Amneal Pharmaceuticals LLC	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	65162080514	Amneal Pharmaceuticals LLC	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	67877054107	Ascend Laboratories, LLC	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	73043001505	Devatis Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	75834014505	Nivagen Pharmaceuticals Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	67877054114	Ascend Laboratories, LLC	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	16571082051	Rising Pharma Holdings Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	47335093072	Sun Pharmaceutical Industries Inc.	$21.4132 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	47335093074	Sun Pharmaceutical Industries Inc.	$21.4132 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	65162080651	Amneal Pharmaceuticals LLC	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	67877054207	Ascend Laboratories, LLC	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	16571082151	Rising Pharma Holdings Inc.	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	16729005153	Accord Healthcare Inc.	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	47335089374	Sun Pharmaceutical Industries Inc.	$20.5332 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	73043001605	Devatis Inc.	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	31722041631	Camber Pharmaceuticals Inc.	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMODAR 5 MG CAPSULE	00085300404	Merck Sharp & Dohme LLC	$17.1708 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 5 MG CAPSULE	00085300403	Merck Sharp & Dohme LLC	$17.1708 per EA	High Outlier	Brand	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	47335092972	Sun Pharmaceutical Industries Inc.	$11.4609 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	65162080414	Amneal Pharmaceuticals LLC	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	67877054014	Ascend Laboratories, LLC	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	16729012954	Accord Healthcare Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	65162080451	Amneal Pharmaceuticals LLC	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	47335092974	Sun Pharmaceutical Industries Inc.	$11.4609 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	67877054007	Ascend Laboratories, LLC	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	16729012953	Accord Healthcare Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	73043001414	Devatis Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	16571081951	Rising Pharma Holdings Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	31722041414	Camber Pharmaceuticals Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	16571081941	Rising Pharma Holdings Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	73043001405	Devatis Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	31722041431	Camber Pharmaceuticals Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	47335092980	Sun Pharmaceutical Industries Inc.	$10.7251 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	47335092921	Sun Pharmaceutical Industries Inc.	$10.7251 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	47335089221	Sun Pharmaceutical Industries Inc.	$8.9168 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	47335089280	Sun Pharmaceutical Industries Inc.	$8.9168 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	75834014414	Nivagen Pharmaceuticals Inc.	$8.3047 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	75834014405	Nivagen Pharmaceuticals Inc.	$8.3047 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	47335089080	Sun Pharmaceutical Industries Inc.	$7.0598 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	47335089021	Sun Pharmaceutical Industries Inc.	$7.0598 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	47335089121	Sun Pharmaceutical Industries Inc.	$4.8083 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	47335089180	Sun Pharmaceutical Industries Inc.	$4.8083 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	16571081841	Rising Pharma Holdings Inc.	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	16571081851	Rising Pharma Holdings Inc.	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	16729005053	Accord Healthcare Inc.	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	16729005054	Accord Healthcare Inc.	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	31722041314	Camber Pharmaceuticals Inc.	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	31722041331	Camber Pharmaceuticals Inc.	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	47335089272	Sun Pharmaceutical Industries Inc.	$4.3755 per EA	High Outlier	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	47335089274	Sun Pharmaceutical Industries Inc.	$4.3755 per EA	High Outlier	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	65162080314	Amneal Pharmaceuticals LLC	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	65162080351	Amneal Pharmaceuticals LLC	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	67877053907	Ascend Laboratories, LLC	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	67877053914	Ascend Laboratories, LLC	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	73043001305	Devatis Inc.	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	73043001314	Devatis Inc.	$4.3755 per EA	—	Generic	-8.10%	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	75834014214	Nivagen Pharmaceuticals Inc.	$4.1124 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	75834014205	Nivagen Pharmaceuticals Inc.	$4.1124 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	31722041131	Camber Pharmaceuticals Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	16571081651	Rising Pharma Holdings Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	16571081641	Rising Pharma Holdings Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	16729004854	Accord Healthcare Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	47335089074	Sun Pharmaceutical Industries Inc.	$1.9313 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	31722041114	Camber Pharmaceuticals Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	73043001105	Devatis Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	67877053707	Ascend Laboratories, LLC	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	73043001114	Devatis Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	47335089072	Sun Pharmaceutical Industries Inc.	$1.9313 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	16729004853	Accord Healthcare Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	67877053714	Ascend Laboratories, LLC	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	65162080151	Amneal Pharmaceuticals LLC	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	65162080114	Amneal Pharmaceuticals LLC	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	31722041231	Camber Pharmaceuticals Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	73043001214	Devatis Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	65162080214	Amneal Pharmaceuticals LLC	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	67877053814	Ascend Laboratories, LLC	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	31722041214	Camber Pharmaceuticals Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	73043001205	Devatis Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	67877053807	Ascend Laboratories, LLC	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	16729004953	Accord Healthcare Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	16729004954	Accord Healthcare Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	47335089174	Sun Pharmaceutical Industries Inc.	$0.8798 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	16571081751	Rising Pharma Holdings Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	16571081741	Rising Pharma Holdings Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	65162080251	Amneal Pharmaceuticals LLC	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	47335089172	Sun Pharmaceutical Industries Inc.	$0.8798 per EA	High Outlier	Generic	—	Alkylating Drug

Frequently Asked Questions

What is Temozolomide used to treat?

Temozolomide is used to treat glioblastoma and melanoma, per the National Library of Medicine's MED-RT classification.

When did Temozolomide become available as a generic?

FDA approved the first generic Temozolomide (ANDA) on Mar 1, 2010. The Orange Book currently lists 58 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How much does Medicare spend on Temozolomide?

In 2024, Medicare Part D spent $39K on Temozolomide across 58 claims for 18 beneficiaries.

How many Temozolomide products are on the market?

The Temozolomide drug market contains 104 NDCs from 9 manufacturers — 93 generic and 11 brand products.

What is the price range for Temozolomide?

NADAC reference prices for Temozolomide range from $0.8798 to $1091.6709 per EA — the most expensive product costs about 1,241× the cheapest.

Is generic Temozolomide cheaper than brand?

The average generic NADAC for Temozolomide is $15.7213 per EA, versus $329.2803 for brand-labeled products — brand versions average about 21× the generic price.

Which manufacturers make Temozolomide?

9 manufacturers list Temozolomide in NADAC. Ranked by number of NDCs, the largest are Sun Pharmaceutical Industries Inc. (21), Merck Sharp & Dohme LLC (11), Accord Healthcare Inc. (11), Rising Pharma Holdings Inc. (11), Camber Pharmaceuticals Inc. (11).

How has the price of Temozolomide changed recently?

Over the past 7 days, 0 Temozolomide NDCs rose and 14 fell, with a market-wide average change of -8.1%.