Temozolomide

104 NDCs across 9 manufacturers|93 Generic,11 Brand

Temozolomide is used to treat glioblastoma and melanoma, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on Aug 11, 1999, and the first generic was approved Mar 1, 2010. FDA's Orange Book lists 58 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $39K on Temozolomide across 58 claims for 18 beneficiaries.

Temozolomide is available as 104 NDCs from 9 manufacturers (93 generic, 11 brand), with NADAC prices from $0.88 to $1091.67 per EA — the most expensive product costs about 1,241× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

104

93G / 11B

Manufacturers

competing in market

Price Spread

$0.88 – $1091.67

per EA

7d Activity

14↓90 flat

avg -4.0% WoW · of 104 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

9 manufacturers producing TEMOZOLOMIDE(2 pricing outliers)

Sun Pharmaceutical Industries Inc.

Merck Sharp & Dohme LLC

Accord Healthcare Inc.

11 NDCs

$9.2205

avg/unit

Rising Pharma Holdings Inc.

11 NDCs

$9.2205

avg/unit

Camber Pharmaceuticals Inc.

Amneal Pharmaceuticals LLC

11 NDCs

$9.2205

avg/unit

Ascend Laboratories, LLC

11 NDCs

$9.2205

avg/unit

Nivagen Pharmaceuticals Inc.

6 NDCs

$11.2768

avg/unit

Drug Portfolio

104 NDCs total, 104 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
TEMODAR 250 MG CAPSULE	00085141702	Merck Sharp & Dohme LLC	$1091.6709 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 180 MG CAPSULE	00085143003	Merck Sharp & Dohme LLC	$634.6595 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 180 MG CAPSULE	00085143004	Merck Sharp & Dohme LLC	$634.6595 per EA	High Outlier	Brand	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	47335093021	Sun Pharmaceutical Industries Inc.	$313.4079 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	47335093080	Sun Pharmaceutical Industries Inc.	$313.4079 per EA	High Outlier	Generic	—	Alkylating Drug
TEMODAR 140 MG CAPSULE	00085142504	Merck Sharp & Dohme LLC	$306.9869 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 140 MG CAPSULE	00085142503	Merck Sharp & Dohme LLC	$306.9869 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 100 MG CAPSULE	00085136604	Merck Sharp & Dohme LLC	$216.4714 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 100 MG CAPSULE	00085136603	Merck Sharp & Dohme LLC	$216.4714 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 20 MG CAPSULE	00085151903	Merck Sharp & Dohme LLC	$89.9177 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 20 MG CAPSULE	00085151904	Merck Sharp & Dohme LLC	$89.9177 per EA	High Outlier	Brand	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	16729013053	Accord Healthcare Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	16571082041	Rising Pharma Holdings Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	75834014514	Nivagen Pharmaceuticals Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	31722041514	Camber Pharmaceuticals Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	16729013054	Accord Healthcare Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	31722041531	Camber Pharmaceuticals Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	73043001514	Devatis Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	65162080551	Amneal Pharmaceuticals LLC	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	65162080514	Amneal Pharmaceuticals LLC	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	67877054107	Ascend Laboratories, LLC	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	73043001505	Devatis Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	75834014505	Nivagen Pharmaceuticals Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	67877054114	Ascend Laboratories, LLC	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	16571082051	Rising Pharma Holdings Inc.	$21.4132 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	47335093072	Sun Pharmaceutical Industries Inc.	$21.4132 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 180 MG CAPSULE	47335093074	Sun Pharmaceutical Industries Inc.	$21.4132 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	65162080651	Amneal Pharmaceuticals LLC	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	67877054207	Ascend Laboratories, LLC	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	16571082151	Rising Pharma Holdings Inc.	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	16729005153	Accord Healthcare Inc.	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	47335089374	Sun Pharmaceutical Industries Inc.	$20.5332 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	73043001605	Devatis Inc.	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 250 MG CAPSULE	31722041631	Camber Pharmaceuticals Inc.	$20.5332 per EA	—	Generic	—	Alkylating Drug
TEMODAR 5 MG CAPSULE	00085300404	Merck Sharp & Dohme LLC	$17.1708 per EA	High Outlier	Brand	—	Alkylating Drug
TEMODAR 5 MG CAPSULE	00085300403	Merck Sharp & Dohme LLC	$17.1708 per EA	High Outlier	Brand	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	47335092972	Sun Pharmaceutical Industries Inc.	$11.4609 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	65162080414	Amneal Pharmaceuticals LLC	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	67877054014	Ascend Laboratories, LLC	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	16729012954	Accord Healthcare Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	65162080451	Amneal Pharmaceuticals LLC	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	47335092974	Sun Pharmaceutical Industries Inc.	$11.4609 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	67877054007	Ascend Laboratories, LLC	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	16729012953	Accord Healthcare Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	73043001414	Devatis Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	16571081951	Rising Pharma Holdings Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	31722041414	Camber Pharmaceuticals Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	16571081941	Rising Pharma Holdings Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	73043001405	Devatis Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	31722041431	Camber Pharmaceuticals Inc.	$11.4609 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	47335092980	Sun Pharmaceutical Industries Inc.	$10.7251 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	47335092921	Sun Pharmaceutical Industries Inc.	$10.7251 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	47335089221	Sun Pharmaceutical Industries Inc.	$8.9168 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	47335089280	Sun Pharmaceutical Industries Inc.	$8.9168 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	75834014414	Nivagen Pharmaceuticals Inc.	$8.3047 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 140 MG CAPSULE	75834014405	Nivagen Pharmaceuticals Inc.	$8.3047 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	47335089080	Sun Pharmaceutical Industries Inc.	$7.0598 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	47335089021	Sun Pharmaceutical Industries Inc.	$7.0598 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	47335089121	Sun Pharmaceutical Industries Inc.	$4.8083 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	47335089180	Sun Pharmaceutical Industries Inc.	$4.8083 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	16571081841	Rising Pharma Holdings Inc.	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	16571081851	Rising Pharma Holdings Inc.	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	16729005053	Accord Healthcare Inc.	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	16729005054	Accord Healthcare Inc.	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	31722041314	Camber Pharmaceuticals Inc.	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	31722041331	Camber Pharmaceuticals Inc.	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	47335089272	Sun Pharmaceutical Industries Inc.	$4.7610 per EA	High Outlier	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	47335089274	Sun Pharmaceutical Industries Inc.	$4.7610 per EA	High Outlier	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	65162080314	Amneal Pharmaceuticals LLC	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	65162080351	Amneal Pharmaceuticals LLC	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	67877053907	Ascend Laboratories, LLC	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	67877053914	Ascend Laboratories, LLC	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	73043001305	Devatis Inc.	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 100 MG CAPSULE	73043001314	Devatis Inc.	$4.7610 per EA	—	Generic	-4.02%	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	75834014214	Nivagen Pharmaceuticals Inc.	$4.1124 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	75834014205	Nivagen Pharmaceuticals Inc.	$4.1124 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	31722041131	Camber Pharmaceuticals Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	16571081651	Rising Pharma Holdings Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	16571081641	Rising Pharma Holdings Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	16729004854	Accord Healthcare Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	47335089074	Sun Pharmaceutical Industries Inc.	$1.9313 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	31722041114	Camber Pharmaceuticals Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	73043001105	Devatis Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	67877053707	Ascend Laboratories, LLC	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	73043001114	Devatis Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	47335089072	Sun Pharmaceutical Industries Inc.	$1.9313 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	16729004853	Accord Healthcare Inc.	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	67877053714	Ascend Laboratories, LLC	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	65162080151	Amneal Pharmaceuticals LLC	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 5 MG CAPSULE	65162080114	Amneal Pharmaceuticals LLC	$1.9313 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	31722041231	Camber Pharmaceuticals Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	73043001214	Devatis Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	65162080214	Amneal Pharmaceuticals LLC	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	67877053814	Ascend Laboratories, LLC	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	31722041214	Camber Pharmaceuticals Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	73043001205	Devatis Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	67877053807	Ascend Laboratories, LLC	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	16729004953	Accord Healthcare Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	16729004954	Accord Healthcare Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	47335089174	Sun Pharmaceutical Industries Inc.	$0.8798 per EA	High Outlier	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	16571081751	Rising Pharma Holdings Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	16571081741	Rising Pharma Holdings Inc.	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	65162080251	Amneal Pharmaceuticals LLC	$0.8798 per EA	—	Generic	—	Alkylating Drug
TEMOZOLOMIDE 20 MG CAPSULE	47335089172	Sun Pharmaceutical Industries Inc.	$0.8798 per EA	High Outlier	Generic	—	Alkylating Drug

Frequently Asked Questions

What is Temozolomide used to treat?

Temozolomide is used to treat glioblastoma and melanoma, per the National Library of Medicine's MED-RT classification.

When did Temozolomide become available as a generic?

FDA approved the first generic Temozolomide (ANDA) on Mar 1, 2010. The Orange Book currently lists 58 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How much does Medicare spend on Temozolomide?

In 2024, Medicare Part D spent $39K on Temozolomide across 58 claims for 18 beneficiaries.

How many Temozolomide products are on the market?

The Temozolomide drug market contains 104 NDCs from 9 manufacturers — 93 generic and 11 brand products.

What is the price range for Temozolomide?

NADAC reference prices for Temozolomide range from $0.8798 to $1091.6709 per EA — the most expensive product costs about 1,241× the cheapest.

Is generic Temozolomide cheaper than brand?

The average generic NADAC for Temozolomide is $15.7793 per EA, versus $329.2803 for brand-labeled products — brand versions average about 21× the generic price.

Which manufacturers make Temozolomide?

9 manufacturers list Temozolomide in NADAC. Ranked by number of NDCs, the largest are Sun Pharmaceutical Industries Inc. (21), Merck Sharp & Dohme LLC (11), Accord Healthcare Inc. (11), Rising Pharma Holdings Inc. (11), Camber Pharmaceuticals Inc. (11).

How has the price of Temozolomide changed recently?

Over the past 7 days, 0 Temozolomide NDCs rose and 14 fell, with a market-wide average change of -4.0%.