Zonisamide
30 NDCs across 12 manufacturers|27 Generic,3 Brand
Zonisamide is used to treat partial epilepsies, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Mar 27, 2000, and the first generic was approved Dec 22, 2005. FDA's Orange Book lists 23 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $39 million on Zonisamide across 421,000 claims for 74,000 beneficiaries.
Zonisamide is available as 30 NDCs from 12 manufacturers (27 generic, 3 brand), with NADAC prices from $0.06 to $15.31 per EA — the most expensive product costs about 247× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
30
27G / 3B
Manufacturers
12
competing in market
Price Spread
$0.06 – $15.31
per EA, 29 of 30 NDCs
7d Activity
avg +0.5% WoW · of 30 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Explore this market from other angles
Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.
Top supplier
Glenmark Pharmaceuticals Inc., USA manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Anti-epileptic Agent class view
See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.
Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
12 manufacturers producing ZONISAMIDE(2 pricing outliers)
Frequently Asked Questions
What is Zonisamide used to treat?
Zonisamide is used to treat partial epilepsies, per the National Library of Medicine's MED-RT classification.
When did Zonisamide become available as a generic?
FDA approved the first generic Zonisamide (ANDA) on Dec 22, 2005. The Orange Book currently lists 23 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Zonisamide?
In 2024, Medicare Part D spent $39 million on Zonisamide across 421,000 claims for 74,000 beneficiaries.
How many Zonisamide products are on the market?
The Zonisamide drug market contains 30 NDCs from 12 manufacturers — 27 generic and 3 brand products.
What is the price range for Zonisamide?
NADAC reference prices for Zonisamide range from $0.0620 to $15.3102 per EA — the most expensive product costs about 247× the cheapest. 1 additional product is priced per a different unit (e.g. liquids per ML) and isn't directly comparable.
Is generic Zonisamide cheaper than brand?
The average generic NADAC for Zonisamide is $0.0928 per EA, versus $13.8112 for brand-labeled products — brand versions average about 149× the generic price.
Which manufacturers make Zonisamide?
12 manufacturers list Zonisamide in NADAC. Ranked by number of NDCs, the largest are Glenmark Pharmaceuticals Inc., USA (4), BluePoint Laboratories (4), Viona Pharmaceuticals Inc. (4), Sun Pharmaceutical Industries Inc. (3), Unichem Pharmaceuticals (USA) Inc. (3).
How has the price of Zonisamide changed recently?
Over the past 7 days, 6 Zonisamide NDCs rose and 18 fell, with a market-wide average change of +0.5%.