This NDC is on FDA's drug shortage list (posted Dec 15, 2021)
Reported reason: Other
Product Information
DEPO-MEDROL 80 MG/ML VIAL is a brand product labeled by Pharmacia & Upjohn Company LLC, priced at $11.5329 per ML under NDC 00009347501. Its NADAC has been published 552 times since Nov 28, 2013.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
80 mg/mL
Manufacturer
Pharmacia & Upjohn Company LLCNDC
00009347501
Classification
Brand
Dosage Form
INJECTION, SUSPENSION
Route
INTRA-ARTICULAR; INTRALESIONAL; INTRAMUSCULAR; SOFT TISSUE
Effective Date
8/19/2026
Active Ingredients
METHYLPREDNISOLONE ACETATEApproval Type
New Drug (NDA)
FDA Application
NDA011757FDA Approved
Before 1982
TE Code
AB
On Market Since
5/28/1959
Pharmacological Classes
Price Statistics
The NADAC for DEPO-MEDROL 80 MG/ML VIAL has been published 552 times since Nov 28, 2013, and over the history we have for it it has risen 17.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $11.5329 per ML |
|---|---|
| All-time high | $18.7112 (Jul 11, 2018) |
| All-time low | $7.3382 (May 21, 2025) |
| 52-week high | $11.5329 |
| 52-week low | $7.8544 |
| Median price | $14.3216 |
| Average price | $13.7695 |
| Largest weekly change | -39.5% (Apr 17, 2024) |
| Weeks tracked | 552 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 6% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DEPO-MEDROL 80 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DEPO-MEDROL 80 MG/ML VIAL, manufactured by Pharmacia & Upjohn Company LLC, is $11.5329 per ML (NDC 00009347501), effective Aug 19, 2026.
How has the price of DEPO-MEDROL 80 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for DEPO-MEDROL 80 MG/ML VIAL has risen 17.3%. It has been tracked across 552 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DEPO-MEDROL 80 MG/ML VIAL?
Since Nov 28, 2013, the NADAC for DEPO-MEDROL 80 MG/ML VIAL has ranged from a low of $7.3382 (May 21, 2025) to a high of $18.7112 (Jul 11, 2018), with a median of $14.3216 per ML.
Are there cheaper alternatives to DEPO-MEDROL 80 MG/ML VIAL?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DEPO-MEDROL 400 MG/5 ML VIAL, is $10.8023 per ML — about 6% below DEPO-MEDROL 80 MG/ML VIAL.
Who manufactures DEPO-MEDROL 80 MG/ML VIAL?
DEPO-MEDROL 80 MG/ML VIAL (NDC 00009347501) is labeled by Pharmacia & Upjohn Company LLC, and CMS classifies it as a brand product.
Is DEPO-MEDROL 80 MG/ML VIAL in shortage?
Yes — NDC 00009347501 is currently listed in FDA's drug shortage database (posted Dec 15, 2021). Reported reason: Other.