Product Information
ESTRING 7.5 MCG/DAY (2 MG) RING is a brand product labeled by Pfizer Inc., priced at $551.1881 per EA under NDC 00013104201. Its NADAC has been published 163 times since Jul 12, 2023.
FDA first approved this application on Apr 26, 1996.
The High Outlier badge above means this manufacturer's average price in the estradiol market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
2 mg/1
Manufacturer
Pfizer Inc.NDC
00013104201
Classification
Brand
Dosage Form
SYSTEM
Route
VAGINAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA020472FDA Approved
4/26/1996
On Market Since
6/5/2023
Pharmacological Classes
Price Statistics
The NADAC for ESTRING 7.5 MCG/DAY (2 MG) RING has been published 163 times since Jul 12, 2023, and over the history we have for it it has risen 8.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $551.1881 per EA |
|---|---|
| All-time high | $552.1545 (May 13, 2026) |
| All-time low | $507.6062 (Sep 20, 2023) |
| 52-week high | $552.1545 |
| 52-week low | $537.4846 |
| Median price | $537.4210 |
| Average price | $531.6343 |
| Largest weekly change | +3.0% (Jan 3, 2024) |
| Weeks tracked | 163 |
| Tracking since | Jul 12, 2023 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the estradiol market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRING 7.5 MCG/DAY (2 MG) RING?
The current National Average Drug Acquisition Cost (NADAC) for ESTRING 7.5 MCG/DAY (2 MG) RING, manufactured by Pfizer Inc., is $551.1881 per EA (NDC 00013104201), effective Aug 19, 2026.
How has the price of ESTRING 7.5 MCG/DAY (2 MG) RING changed over time?
Over the history we have for it, the NADAC for ESTRING 7.5 MCG/DAY (2 MG) RING has risen 8.6%. It has been tracked across 163 weekly CMS publications since Jul 12, 2023.
What are the highest and lowest recorded NADAC prices for ESTRING 7.5 MCG/DAY (2 MG) RING?
Since Jul 12, 2023, the NADAC for ESTRING 7.5 MCG/DAY (2 MG) RING has ranged from a low of $507.6062 (Sep 20, 2023) to a high of $552.1545 (May 13, 2026), with a median of $537.4210 per EA.
Are there cheaper alternatives to ESTRING 7.5 MCG/DAY (2 MG) RING?
No other NADAC-published product currently shares the active ingredient and strength of ESTRING 7.5 MCG/DAY (2 MG) RING in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ESTRING 7.5 MCG/DAY (2 MG) RING?
ESTRING 7.5 MCG/DAY (2 MG) RING (NDC 00013104201) is labeled by Pfizer Inc., and CMS classifies it as a brand product.