Product Information
COMBIGAN 0.2%-0.5% EYE DROPS is a brand product labeled by Allergan, Inc., priced at $39.0966 per ML under NDC 00023921110. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Oct 30, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2; 5 mg/mL; mg/mL
Manufacturer
Allergan, Inc.NDC
00023921110
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
BRIMONIDINE TARTRATE; TIMOLOL MALEATEApproval Type
New Drug (NDA)
FDA Application
NDA021398FDA Approved
10/30/2007
TE Code
AB
On Market Since
11/14/2007
Pharmacological Classes
Price Statistics
The NADAC for COMBIGAN 0.2%-0.5% EYE DROPS has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 116.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $39.0966 per ML |
|---|---|
| All-time high | $39.2512 (Mar 13, 2024) |
| All-time low | $18.0995 (Nov 28, 2013) |
| 52-week high | $39.2013 |
| 52-week low | $39.0966 |
| Median price | $35.5620 |
| Average price | $32.7517 |
| Largest weekly change | +9.9% (Jan 13, 2016) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of COMBIGAN 0.2%-0.5% EYE DROPS?
The current National Average Drug Acquisition Cost (NADAC) for COMBIGAN 0.2%-0.5% EYE DROPS, manufactured by Allergan, Inc., is $39.0966 per ML (NDC 00023921110), effective Aug 19, 2026.
How has the price of COMBIGAN 0.2%-0.5% EYE DROPS changed over time?
Over the history we have for it, the NADAC for COMBIGAN 0.2%-0.5% EYE DROPS has risen 116.0%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for COMBIGAN 0.2%-0.5% EYE DROPS?
Since Nov 28, 2013, the NADAC for COMBIGAN 0.2%-0.5% EYE DROPS has ranged from a low of $18.0995 (Nov 28, 2013) to a high of $39.2512 (Mar 13, 2024), with a median of $35.5620 per ML.
Are there cheaper alternatives to COMBIGAN 0.2%-0.5% EYE DROPS?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, COMBIGAN 0.2%-0.5% EYE DROPS, is $39.0886 per ML — about 0% below COMBIGAN 0.2%-0.5% EYE DROPS.
Who manufactures COMBIGAN 0.2%-0.5% EYE DROPS?
COMBIGAN 0.2%-0.5% EYE DROPS (NDC 00023921110) is labeled by Allergan, Inc., and CMS classifies it as a brand product.