Product Information
COMBIGAN 0.2%-0.5% EYE DROPS is a brand product labeled by Allergan, Inc., priced at $39.0913 per ML under NDC 00023921115. Its NADAC has been published 511 times since Dec 21, 2016.
FDA first approved this application on Oct 30, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2; 5 mg/mL; mg/mL
Manufacturer
Allergan, Inc.NDC
00023921115
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
BRIMONIDINE TARTRATE; TIMOLOL MALEATEApproval Type
New Drug (NDA)
FDA Application
NDA021398FDA Approved
10/30/2007
TE Code
AB
On Market Since
11/14/2007
Pharmacological Classes
Price Statistics
The NADAC for COMBIGAN 0.2%-0.5% EYE DROPS has been published 511 times since Dec 21, 2016, and over the history we have for it it has risen 51.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $39.0913 per ML |
|---|---|
| All-time high | $39.3534 (Mar 13, 2024) |
| All-time low | $25.8322 (Dec 21, 2016) |
| 52-week high | $39.1760 |
| 52-week low | $39.0886 |
| Median price | $37.3503 |
| Average price | $36.0832 |
| Largest weekly change | +9.5% (Jan 11, 2017) |
| Weeks tracked | 511 |
| Tracking since | Dec 21, 2016 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Allergan, Inc. manufacturer profile
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Drug market
brimonidine tartrate, timolol maleate market comparison
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Therapeutic class
alpha-Adrenergic Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of COMBIGAN 0.2%-0.5% EYE DROPS?
The current National Average Drug Acquisition Cost (NADAC) for COMBIGAN 0.2%-0.5% EYE DROPS, manufactured by Allergan, Inc., is $39.0913 per ML (NDC 00023921115), effective Sep 30, 2026.
How has the price of COMBIGAN 0.2%-0.5% EYE DROPS changed over time?
Over the history we have for it, the NADAC for COMBIGAN 0.2%-0.5% EYE DROPS has risen 51.3%. It has been tracked across 511 weekly CMS publications since Dec 21, 2016.
What are the highest and lowest recorded NADAC prices for COMBIGAN 0.2%-0.5% EYE DROPS?
Since Dec 21, 2016, the NADAC for COMBIGAN 0.2%-0.5% EYE DROPS has ranged from a low of $25.8322 (Dec 21, 2016) to a high of $39.3534 (Mar 13, 2024), with a median of $37.3503 per ML.
Are there cheaper alternatives to COMBIGAN 0.2%-0.5% EYE DROPS?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as COMBIGAN 0.2%-0.5% EYE DROPS in a comparable dosage form, but none are currently priced below it.
Who manufactures COMBIGAN 0.2%-0.5% EYE DROPS?
COMBIGAN 0.2%-0.5% EYE DROPS (NDC 00023921115) is labeled by Allergan, Inc., and CMS classifies it as a brand product.