Product Information
LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM is a generic product labeled by PAI Holdings LLC, priced at $0.2164 per GM under NDC 00121100230. Its NADAC has been published 55 times since Jun 11, 2025.
Strength
25; 25 mg/g; mg/g
Manufacturer
PAI Holdings LLCNDC
00121100230
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
LIDOCAINE; PRILOCAINEApproval Type
Generic (ANDA)
FDA Application
ANDA205887On Market Since
2/6/2025
Pharmacological Classes
Price Statistics
The NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has been published 55 times since Jun 11, 2025, and over the history we have for it it has declined 22.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2164 per GM |
|---|---|
| All-time high | $0.2791 (Jun 11, 2025) |
| All-time low | $0.2164 (Jun 17, 2026) |
| 52-week high | $0.2756 |
| 52-week low | $0.2164 |
| Median price | $0.2698 |
| Average price | $0.2583 |
| Largest weekly change | -6.4% (Mar 18, 2026) |
| Weeks tracked | 55 |
| Tracking since | Jun 11, 2025 |
Generic Alternatives
The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM, manufactured by PAI Holdings LLC, is $0.2164 per GM (NDC 00121100230), effective Jun 24, 2026.
How has the price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM changed over time?
Over the history we have for it, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has declined 22.5%. It has been tracked across 55 weekly CMS publications since Jun 11, 2025.
What are the highest and lowest recorded NADAC prices for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
Since Jun 11, 2025, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has ranged from a low of $0.2164 (Jun 17, 2026) to a high of $0.2791 (Jun 11, 2025), with a median of $0.2698 per GM.
Are there cheaper alternatives to LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
2 NADAC-published products share the same active ingredient, strength, and dosage form as LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM, but none are currently priced below it.
Who manufactures LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM (NDC 00121100230) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.
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