Product Information

BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET is a generic product labeled by PAI Holdings LLC, priced at $0.4123 per EA under NDC 00121101830. Its NADAC has been published 121 times since Mar 6, 2024.

BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET

buprenorphine hydrochloride and naloxone hydrochloride
$0.4123per EA
DEA Schedule CIII

Strength

2; .5 mg/1; mg/1

Manufacturer

PAI Holdings LLC

NDC

00121101830

Classification

Generic

Dosage Form

TABLET

Route

SUBLINGUAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA204431

On Market Since

9/5/2023

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists
Partial Opioid Agonist
Partial Opioid Agonists

Price Statistics

The NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has been published 121 times since Mar 6, 2024, and over the history we have for it it has declined 23.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4123 per EA
All-time high$0.6796 (Apr 10, 2024)
All-time low$0.3740 (Nov 20, 2024)
52-week high$0.5463
52-week low$0.4123
Median price$0.4879
Average price$0.5000
Largest weekly change+58.5% (Aug 21, 2024)
Weeks tracked121
Tracking sinceMar 6, 2024

Price History

1W

0.0%

1M

-4.4%

3M

-14.3%

6M

-13.0%

1Y

-20.9%

3Y

N/A

5Y

N/A

All

-23.4%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the buprenorphine hydrochloride and naloxone hydrochloride market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET, manufactured by PAI Holdings LLC, is $0.4123 per EA (NDC 00121101830), effective Jun 24, 2026.

How has the price of BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET changed over time?

Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has declined 23.4%. It has been tracked across 121 weekly CMS publications since Mar 6, 2024.

What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

Since Mar 6, 2024, the NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has ranged from a low of $0.3740 (Nov 20, 2024) to a high of $0.6796 (Apr 10, 2024), with a median of $0.4879 per EA.

Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET, so no direct lower-cost alternative is listed.

Who manufactures BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET (NDC 00121101830) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.