Product Information

ESTRADIOL VALERATE 50 MG/5 ML is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $18.2988 per ML under NDC 00143928901. Its NADAC has been published 129 times since Apr 17, 2024.

FDA first approved this application on Apr 21, 2020. Its Orange Book therapeutic-equivalence code is AO.

ESTRADIOL VALERATE 50 MG/5 ML

Estradiol Valerate
$18.2988per ML

Strength

10 mg/mL

NDC

00143928901

Classification

Generic

Dosage Form

INJECTION

Route

INTRAMUSCULAR

Effective Date

9/23/2026

Active Ingredients

ESTRADIOL VALERATE

Approval Type

Generic (ANDA)

FDA Application

ANDA203723

FDA Approved

4/21/2020

TE Code

AO

On Market Since

4/21/2020

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for ESTRADIOL VALERATE 50 MG/5 ML has been published 129 times since Apr 17, 2024, and over the history we have for it it has risen 9.7%. The table below summarizes its recorded NADAC range and movement.

Current price$18.2988 per ML
All-time high$19.3574 (Apr 15, 2026)
All-time low$15.7509 (Jul 17, 2024)
52-week high$19.3574
52-week low$17.2246
Median price$16.8870
Average price$17.3011
Largest weekly change+3.4% (Jan 21, 2026)
Weeks tracked129
Tracking sinceApr 17, 2024

Price History

1W

0.0%

1M

+0.2%

3M

+0.3%

6M

-5.5%

1Y

+6.2%

3Y

N/A

5Y

N/A

All

+9.7%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Estradiol Valerate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Continue researching this drug

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Frequently asked questions

What is the NADAC price of ESTRADIOL VALERATE 50 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL VALERATE 50 MG/5 ML, manufactured by Hikma Pharmaceuticals USA Inc., is $18.2988 per ML (NDC 00143928901), effective Sep 30, 2026.

How has the price of ESTRADIOL VALERATE 50 MG/5 ML changed over time?

Over the history we have for it, the NADAC for ESTRADIOL VALERATE 50 MG/5 ML has risen 9.7%. It has been tracked across 129 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for ESTRADIOL VALERATE 50 MG/5 ML?

Since Apr 17, 2024, the NADAC for ESTRADIOL VALERATE 50 MG/5 ML has ranged from a low of $15.7509 (Jul 17, 2024) to a high of $19.3574 (Apr 15, 2026), with a median of $16.8870 per ML.

Are there cheaper alternatives to ESTRADIOL VALERATE 50 MG/5 ML?

No other NADAC-published product currently shares the active ingredient and strength of ESTRADIOL VALERATE 50 MG/5 ML in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures ESTRADIOL VALERATE 50 MG/5 ML?

ESTRADIOL VALERATE 50 MG/5 ML (NDC 00143928901) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.