Estradiol Valerate
10 NDCs across 4 manufacturers|8 Generic,2 Brand
Estradiol Valerate is used to treat breast neoplasms, hot flashes, hypogonadism, premature menopause, menorrhagia and primary ovarian insufficiency, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Jan 1, 1982. In 2024, Medicare Part D spent $2 million on Estradiol Valerate across 15,000 claims for 4,782 beneficiaries.
Estradiol Valerate is available as 10 NDCs from 4 manufacturers (8 generic, 2 brand), with NADAC prices from $18.30 to $36.83 per ML — the most expensive product costs about 2.0× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
10
8G / 2B
Manufacturers
4
competing in market
Price Spread
$18.30 – $36.83
per ML
7d Activity
avg +3.1% WoW · of 10 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Xiromed LLC manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Estrogen class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
4 manufacturers producing ESTRADIOL VALERATE
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
ESTRADIOL VALERATE 200 MG/5 ML | $36.8279 per ML | +5.04% |
ESTRADIOL VALERATE 200 MG/5 ML | $36.8279 per ML | +5.04% |
ESTRADIOL VALERATE 200 MG/5 ML | $36.8279 per ML | +5.04% |
DELESTROGEN 100 MG/5 ML VIAL | $35.7527 per ML | +0.04% |
DELESTROGEN 50 MG/5 ML VIAL | $25.5049 per ML | +0.02% |
ESTRADIOL VALERATE 100 MG/5 ML | $22.6452 per ML | +5.14% |
ESTRADIOL VALERATE 100 MG/5 ML | $22.6452 per ML | +5.14% |
ESTRADIOL VALERATE 100 MG/5 ML | $22.6452 per ML | +5.14% |
ESTRADIOL VALERATE 50 MG/5 ML | $18.2988 per ML | +0.20% |
ESTRADIOL VALERATE 50 MG/5 ML | $18.2988 per ML | +0.20% |
Frequently Asked Questions
What is Estradiol Valerate used to treat?
Estradiol Valerate is used to treat breast neoplasms, hot flashes, hypogonadism, premature menopause, menorrhagia and primary ovarian insufficiency, per the National Library of Medicine's MED-RT classification.
When did Estradiol Valerate become available as a generic?
FDA approved the first generic Estradiol Valerate (ANDA) on Jan 1, 1982.
How much does Medicare spend on Estradiol Valerate?
In 2024, Medicare Part D spent $2 million on Estradiol Valerate across 15,000 claims for 4,782 beneficiaries.
How many Estradiol Valerate products are on the market?
The Estradiol Valerate drug market contains 10 NDCs from 4 manufacturers — 8 generic and 2 brand products.
What is the price range for Estradiol Valerate?
NADAC reference prices for Estradiol Valerate range from $18.2988 to $36.8279 per ML — the most expensive product costs about 2.0× the cheapest.
Is generic Estradiol Valerate cheaper than brand?
The average generic NADAC for Estradiol Valerate is $26.8771 per ML, versus $30.6288 for brand-labeled products — generic is about 12% cheaper on average.
Which manufacturers make Estradiol Valerate?
4 manufacturers list Estradiol Valerate in NADAC. Ranked by number of NDCs, the largest are Xiromed LLC (3), Hikma Pharmaceuticals USA Inc. (3), American Regent, Inc. (2), Par Health USA, LLC (2).
How has the price of Estradiol Valerate changed recently?
Over the past 7 days, 10 Estradiol Valerate NDCs rose and 0 fell, with a market-wide average change of +3.1%.