Product Information
DAPTOMYCIN 500 MG VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $21.6249 per EA under NDC 00143937801. Its NADAC has been published 59 times since Apr 17, 2024.
FDA first approved this application on Aug 22, 2019.
Strength
500 mg/10mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00143937801
Classification
Generic
Dosage Form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Effective Date
5/21/2025
Active Ingredients
DAPTOMYCINApproval Type
Generic (ANDA)
FDA Application
ANDA212022FDA Approved
8/22/2019
On Market Since
1/1/2020
Pharmacological Classes
Price Statistics
The NADAC for DAPTOMYCIN 500 MG VIAL has been published 59 times since Apr 17, 2024, and over the history we have for it it has declined 13.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $21.6249 per EA |
|---|---|
| All-time high | $28.3900 (Sep 11, 2024) |
| All-time low | $20.1865 (Apr 23, 2025) |
| Median price | $24.8289 |
| Average price | $23.8720 |
| Largest weekly change | +10.7% (Aug 21, 2024) |
| Weeks tracked | 59 |
| Tracking since | Apr 17, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
N/A
5Y
N/A
All
-13.0%
Last surveyed May 28, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Hikma Pharmaceuticals USA Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Daptomycin market comparison
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Therapeutic class
Lipopeptide Antibacterial class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DAPTOMYCIN 500 MG VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DAPTOMYCIN 500 MG VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $21.6249 per EA (NDC 00143937801), effective May 28, 2025.
How has the price of DAPTOMYCIN 500 MG VIAL changed over time?
Over the history we have for it, the NADAC for DAPTOMYCIN 500 MG VIAL has declined 13.0%. It has been tracked across 59 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for DAPTOMYCIN 500 MG VIAL?
Since Apr 17, 2024, the NADAC for DAPTOMYCIN 500 MG VIAL has ranged from a low of $20.1865 (Apr 23, 2025) to a high of $28.3900 (Sep 11, 2024), with a median of $24.8289 per EA.
Are there cheaper alternatives to DAPTOMYCIN 500 MG VIAL?
Yes. 12 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DAPTOMYCIN 500 MG VIAL, is $20.7686 per EA — about 4% below DAPTOMYCIN 500 MG VIAL.
Who manufactures DAPTOMYCIN 500 MG VIAL?
DAPTOMYCIN 500 MG VIAL (NDC 00143937801) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.