Product Information
DAPTOMYCIN 500 MG VIAL is a generic product labeled by Accord Healthcare Inc., priced at $21.8463 per EA under NDC 16729043505. Its NADAC has been published 110 times since Apr 17, 2024.
FDA first approved this application on Jun 24, 2019. Its Orange Book therapeutic-equivalence code is AP.
Strength
500 mg/10mL
Manufacturer
Accord Healthcare Inc.NDC
16729043505
Classification
Generic
Dosage Form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Effective Date
5/20/2026
Active Ingredients
DAPTOMYCINApproval Type
Generic (ANDA)
FDA Application
ANDA211961FDA Approved
6/24/2019
TE Code
AP
On Market Since
6/24/2019
Pharmacological Classes
Price Statistics
The NADAC for DAPTOMYCIN 500 MG VIAL has been published 110 times since Apr 17, 2024, and over the history we have for it it has declined 12.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $21.8463 per EA |
|---|---|
| All-time high | $28.3900 (Sep 11, 2024) |
| All-time low | $20.1020 (Oct 22, 2025) |
| 52-week high | $24.2743 |
| 52-week low | $20.1020 |
| Median price | $22.1643 |
| Average price | $22.8899 |
| Largest weekly change | -17.2% (Oct 22, 2025) |
| Weeks tracked | 110 |
| Tracking since | Apr 17, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
+5.2%
1Y
-10.0%
3Y
N/A
5Y
N/A
All
-12.1%
Last surveyed May 20, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 5% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DAPTOMYCIN 500 MG VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DAPTOMYCIN 500 MG VIAL, manufactured by Accord Healthcare Inc., is $21.8463 per EA (NDC 16729043505), effective May 20, 2026.
How has the price of DAPTOMYCIN 500 MG VIAL changed over time?
Over the history we have for it, the NADAC for DAPTOMYCIN 500 MG VIAL has declined 12.1%. It has been tracked across 110 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for DAPTOMYCIN 500 MG VIAL?
Since Apr 17, 2024, the NADAC for DAPTOMYCIN 500 MG VIAL has ranged from a low of $20.1020 (Oct 22, 2025) to a high of $28.3900 (Sep 11, 2024), with a median of $22.1643 per EA.
Are there cheaper alternatives to DAPTOMYCIN 500 MG VIAL?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DAPTOMYCIN 500 MG VIAL, is $20.7686 per EA — about 5% below DAPTOMYCIN 500 MG VIAL.
Who manufactures DAPTOMYCIN 500 MG VIAL?
DAPTOMYCIN 500 MG VIAL (NDC 16729043505) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.