Product Information

LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM is a generic product labeled by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., priced at $0.2211 per GM under NDC 00168035730. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Aug 18, 2003. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM

lidocaine and prilocaine
$0.2211per GM

Strength

25; 25 mg/g; mg/g

NDC

00168035730

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

LIDOCAINE; PRILOCAINE

Approval Type

Generic (ANDA)

FDA Application

ANDA076453

FDA Approved

8/18/2003

TE Code

AB

On Market Since

8/18/2003

Pharmacological Classes

Amide Local Anesthetic
Amide Local Anesthetic
Amides
Amides
Antiarrhythmic
Local Anesthesia
Local Anesthesia

Price Statistics

The NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 51.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2211 per GM
All-time high$1.2008 (Feb 11, 2015)
All-time low$0.2164 (Jun 17, 2026)
52-week high$0.2733
52-week low$0.2164
Median price$0.3611
Average price$0.4503
Largest weekly change+46.1% (Feb 16, 2022)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+1.3%

1M

+1.3%

3M

+1.2%

6M

-13.6%

1Y

-18.4%

3Y

-48.7%

5Y

-8.2%

All

-51.9%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM, manufactured by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., is $0.2211 per GM (NDC 00168035730), effective Aug 19, 2026.

How has the price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM changed over time?

Over the history we have for it, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has declined 51.9%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

Since Nov 28, 2013, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has ranged from a low of $0.2164 (Jun 17, 2026) to a high of $1.2008 (Feb 11, 2015), with a median of $0.3611 per GM.

Are there cheaper alternatives to LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM in a comparable dosage form, but none are currently priced below it.

Who manufactures LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM (NDC 00168035730) is labeled by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., and CMS classifies it as a generic product.