Product Information
LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM is a generic product labeled by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., priced at $0.2317 per GM under NDC 00168035730. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Aug 18, 2003. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25; 25 mg/g; mg/g
NDC
00168035730
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
LIDOCAINE; PRILOCAINEApproval Type
Generic (ANDA)
FDA Application
ANDA076453FDA Approved
8/18/2003
TE Code
AB
On Market Since
8/18/2003
Pharmacological Classes
Price Statistics
The NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 49.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2317 per GM |
|---|---|
| All-time high | $1.2008 (Feb 11, 2015) |
| All-time low | $0.2164 (Jun 17, 2026) |
| 52-week high | $0.2733 |
| 52-week low | $0.2164 |
| Median price | $0.3534 |
| Average price | $0.4483 |
| Largest weekly change | +46.1% (Feb 16, 2022) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
E. Fougera & Co. a division of Fougera Pharmaceuticals Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
lidocaine and prilocaine market comparison
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Therapeutic class
Amide Local Anesthetic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM, manufactured by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., is $0.2317 per GM (NDC 00168035730), effective Sep 30, 2026.
How has the price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM changed over time?
Over the history we have for it, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has declined 49.6%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
Since Nov 28, 2013, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has ranged from a low of $0.2164 (Jun 17, 2026) to a high of $1.2008 (Feb 11, 2015), with a median of $0.3534 per GM.
Are there cheaper alternatives to LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM (NDC 00168035730) is labeled by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., and CMS classifies it as a generic product.