Product Information
LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM is a generic product labeled by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., priced at $1.3353 per GM under NDC 00168035755. Its NADAC has been published 466 times since Jan 22, 2014.
FDA first approved this application on Aug 18, 2003. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25; 25 mg/g; mg/g
NDC
00168035755
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
7/22/2026
Active Ingredients
LIDOCAINE; PRILOCAINEApproval Type
Generic (ANDA)
FDA Application
ANDA076453FDA Approved
8/18/2003
TE Code
AB
On Market Since
8/18/2003
Pharmacological Classes
Price Statistics
The NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has been published 466 times since Jan 22, 2014, and over the history we have for it it has risen 12.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3353 per GM |
|---|---|
| All-time high | $1.5054 (Dec 10, 2025) |
| All-time low | $0.5175 (Jun 19, 2019) |
| 52-week high | $1.5054 |
| 52-week low | $1.3340 |
| Median price | $0.9715 |
| Average price | $0.9681 |
| Largest weekly change | +79.0% (Jan 19, 2022) |
| Weeks tracked | 466 |
| Tracking since | Jan 22, 2014 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 83% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM, manufactured by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., is $1.3353 per GM (NDC 00168035755), effective Aug 19, 2026.
How has the price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM changed over time?
Over the history we have for it, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has risen 12.8%. It has been tracked across 466 weekly CMS publications since Jan 22, 2014.
What are the highest and lowest recorded NADAC prices for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
Since Jan 22, 2014, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has ranged from a low of $0.5175 (Jun 19, 2019) to a high of $1.5054 (Dec 10, 2025), with a median of $0.9715 per GM.
Are there cheaper alternatives to LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM, is $0.2211 per GM — about 83% below LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM.
Who manufactures LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?
LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM (NDC 00168035755) is labeled by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., and CMS classifies it as a generic product.