Back to Market Feed

Product Information

DUOBRII 0.01%-0.045% LOTION is a brand product labeled by Bausch Health US LLC, priced at $10.0097 per GM under NDC 00187065301. Its NADAC has been published 308 times since Sep 18, 2019.

FDA first approved this application on Apr 25, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DUOBRII 0.01%-0.045% LOTION

halobetasol propionate and tazarotene
$10.0097per GM

Strength

.1; .45 mg/g; mg/g

NDC

00187065301

Classification

Brand

Dosage Form

LOTION

Route

TOPICAL

Effective Date

9/17/2025

Approval Type

New Drug (NDA)

FDA Application

NDA209354

FDA Approved

4/25/2019

TE Code

AB

On Market Since

4/25/2019

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid
Retinoid
Retinoids

Price Statistics

The NADAC for DUOBRII 0.01%-0.045% LOTION has been published 308 times since Sep 18, 2019, and over the history we have for it it has risen 25.9%. The table below summarizes its recorded NADAC range and movement.

Current price$10.0097 per GM
All-time high$10.0693 (Jul 16, 2025)
All-time low$7.8918 (Nov 18, 2020)
52-week high$10.0227
52-week low$10.0097
Median price$8.9221
Average price$9.0790
Largest weekly change+8.8% (Jan 11, 2023)
Weeks tracked308
Tracking sinceSep 18, 2019

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

-0.1%

3Y

+3.1%

5Y

+19.7%

All

+25.9%

Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the halobetasol propionate and tazarotene market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Related Drugs

Same classification

PREPARATION H HC 1% CREAM
Brand
00573283010•Haleon US Holdings LLC
$0.2072
per GM
DERMA-SMOOTHE-FS SCALP OIL
Brand
68791010204•Royal Pharmaceuticals
$0.2421
per ML
DERMA-SMOOTHE-FS BODY OIL
Brand
68791010104•Royal Pharmaceuticals
$0.2424
per ML
MEDROL 4 MG TABLET
Brand
00009005602•Pharmacia & Upjohn Company LLC
$0.2454
per EA
MEDROL 4 MG DOSEPAK
Brand
00009005604•Pharmacia & Upjohn Company LLC
$0.2908
per EA
DIFFERIN 0.1% GEL
Brand
00299491045•Galderma Laboratories, L.P.
$0.4639
per GM
DIFFERIN 0.1% GEL
Brand
00299491015•Galderma Laboratories, L.P.
$0.7045
per GM
RETIN-A 0.05% CREAM
Brand
00187516245•Bausch Health US LLC
$0.7904
per GM
RETIN-A 0.025% CREAM
Brand
00187516045•Bausch Health US LLC
$0.7904
per GM
RETIN-A 0.025% CREAM
Brand
00187516020•Bausch Health US LLC
$0.7907
per GM

Frequently asked questions

What is the NADAC price of DUOBRII 0.01%-0.045% LOTION?

The current National Average Drug Acquisition Cost (NADAC) for DUOBRII 0.01%-0.045% LOTION, manufactured by Bausch Health US LLC, is $10.0097 per GM (NDC 00187065301), effective Oct 1, 2025.

How has the price of DUOBRII 0.01%-0.045% LOTION changed over time?

Over the history we have for it, the NADAC for DUOBRII 0.01%-0.045% LOTION has risen 25.9%. It has been tracked across 308 weekly CMS publications since Sep 18, 2019.

What are the highest and lowest recorded NADAC prices for DUOBRII 0.01%-0.045% LOTION?

Since Sep 18, 2019, the NADAC for DUOBRII 0.01%-0.045% LOTION has ranged from a low of $7.8918 (Nov 18, 2020) to a high of $10.0693 (Jul 16, 2025), with a median of $8.9221 per GM.

Are there cheaper alternatives to DUOBRII 0.01%-0.045% LOTION?

No other NADAC-published product currently shares the active ingredient and strength of DUOBRII 0.01%-0.045% LOTION in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures DUOBRII 0.01%-0.045% LOTION?

DUOBRII 0.01%-0.045% LOTION (NDC 00187065301) is labeled by Bausch Health US LLC, and CMS classifies it as a brand product.