Product Information
DUOBRII 0.01%-0.045% LOTION is a brand product labeled by Bausch Health US LLC, priced at $10.0097 per GM under NDC 00187065301. Its NADAC has been published 308 times since Sep 18, 2019.
FDA first approved this application on Apr 25, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.1; .45 mg/g; mg/g
Manufacturer
Bausch Health US LLCNDC
00187065301
Classification
Brand
Dosage Form
LOTION
Route
TOPICAL
Effective Date
9/17/2025
Active Ingredients
HALOBETASOL PROPIONATE; TAZAROTENEApproval Type
New Drug (NDA)
FDA Application
NDA209354FDA Approved
4/25/2019
TE Code
AB
On Market Since
4/25/2019
Pharmacological Classes
Price Statistics
The NADAC for DUOBRII 0.01%-0.045% LOTION has been published 308 times since Sep 18, 2019, and over the history we have for it it has risen 25.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $10.0097 per GM |
|---|---|
| All-time high | $10.0693 (Jul 16, 2025) |
| All-time low | $7.8918 (Nov 18, 2020) |
| Median price | $8.9221 |
| Average price | $9.0790 |
| Largest weekly change | +8.8% (Jan 11, 2023) |
| Weeks tracked | 308 |
| Tracking since | Sep 18, 2019 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
+3.1%
5Y
+19.7%
All
+25.9%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the halobetasol propionate and tazarotene market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Bausch Health US LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
halobetasol propionate and tazarotene market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Corticosteroid class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DUOBRII 0.01%-0.045% LOTION?
The current National Average Drug Acquisition Cost (NADAC) for DUOBRII 0.01%-0.045% LOTION, manufactured by Bausch Health US LLC, is $10.0097 per GM (NDC 00187065301), effective Oct 1, 2025.
How has the price of DUOBRII 0.01%-0.045% LOTION changed over time?
Over the history we have for it, the NADAC for DUOBRII 0.01%-0.045% LOTION has risen 25.9%. It has been tracked across 308 weekly CMS publications since Sep 18, 2019.
What are the highest and lowest recorded NADAC prices for DUOBRII 0.01%-0.045% LOTION?
Since Sep 18, 2019, the NADAC for DUOBRII 0.01%-0.045% LOTION has ranged from a low of $7.8918 (Nov 18, 2020) to a high of $10.0693 (Jul 16, 2025), with a median of $8.9221 per GM.
Are there cheaper alternatives to DUOBRII 0.01%-0.045% LOTION?
No other NADAC-published product currently shares the active ingredient and strength of DUOBRII 0.01%-0.045% LOTION in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures DUOBRII 0.01%-0.045% LOTION?
DUOBRII 0.01%-0.045% LOTION (NDC 00187065301) is labeled by Bausch Health US LLC, and CMS classifies it as a brand product.