Historical record - last NADAC effective date: 3/20/2019

Product Information

DIFFERIN 0.1% GEL is a brand product labeled by Galderma Laboratories, L.P., priced at $0.7045 per GM under NDC 00299491015. Its NADAC has been published 134 times since Aug 23, 2017.

FDA first approved this application on Jul 8, 2016.

The High Outlier badge above means this manufacturer's average price in the Adapalene market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

DIFFERIN 0.1% GEL

Adapalene
$0.7045per GM
High Outlier
OTC

Strength

1 mg/g

NDC

00299491015

Classification

Brand

Dosage Form

GEL

Route

TOPICAL

Effective Date

3/20/2019

Active Ingredients

ADAPALENE

Approval Type

New Drug (NDA)

FDA Application

NDA020380

FDA Approved

7/8/2016

On Market Since

7/8/2016

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for DIFFERIN 0.1% GEL has been published 134 times since Aug 23, 2017, and over the history we have for it it has risen 9.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.7045 per GM
All-time high$0.7045 (Mar 11, 2020)
All-time low$0.6431 (Aug 23, 2017)
Median price$0.6916
Average price$0.6832
Largest weekly change+6.4% (Mar 20, 2019)
Weeks tracked134
Tracking sinceAug 23, 2017

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

N/A

5Y

N/A

All

+9.6%

Last surveyed Mar 11, 2020 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 52% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIFFERIN 0.1% GEL?

The current National Average Drug Acquisition Cost (NADAC) for DIFFERIN 0.1% GEL, manufactured by Galderma Laboratories, L.P., is $0.7045 per GM (NDC 00299491015), effective Mar 11, 2020.

How has the price of DIFFERIN 0.1% GEL changed over time?

Over the history we have for it, the NADAC for DIFFERIN 0.1% GEL has risen 9.6%. It has been tracked across 134 weekly CMS publications since Aug 23, 2017.

What are the highest and lowest recorded NADAC prices for DIFFERIN 0.1% GEL?

Since Aug 23, 2017, the NADAC for DIFFERIN 0.1% GEL has ranged from a low of $0.6431 (Aug 23, 2017) to a high of $0.7045 (Mar 11, 2020), with a median of $0.6916 per GM.

Are there cheaper alternatives to DIFFERIN 0.1% GEL?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ADAPALENE 0.1% GEL, is $0.3380 per GM — about 52% below DIFFERIN 0.1% GEL.

Who manufactures DIFFERIN 0.1% GEL?

DIFFERIN 0.1% GEL (NDC 00299491015) is labeled by Galderma Laboratories, L.P., and CMS classifies it as a brand product.