Product Information
RETIN-A 0.025% CREAM is a brand product labeled by Bausch Health US LLC, priced at $0.7904 per GM under NDC 00187516045. Its NADAC has been published 390 times since Apr 18, 2018.
FDA first approved this application on Sep 16, 1988. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.25 mg/g
Manufacturer
Bausch Health US LLCNDC
00187516045
Classification
Brand
Dosage Form
CREAM
Route
TOPICAL
Effective Date
7/28/2025
Active Ingredients
TRETINOINApproval Type
New Drug (NDA)
FDA Application
NDA019049FDA Approved
9/16/1988
TE Code
AB
On Market Since
10/30/1988
Pharmacological Classes
Price Statistics
The NADAC for RETIN-A 0.025% CREAM has been published 390 times since Apr 18, 2018, and over the history we have for it it has declined 85.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.7904 per GM |
|---|---|
| All-time high | $5.3213 (Mar 6, 2019) |
| All-time low | $0.7179 (Feb 22, 2023) |
| 52-week high | $0.7904 |
| 52-week low | $0.7904 |
| Median price | $1.6832 |
| Average price | $1.8132 |
| Largest weekly change | -61.9% (Mar 13, 2019) |
| Weeks tracked | 390 |
| Tracking since | Apr 18, 2018 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
+10.1%
5Y
-53.2%
All
-85.1%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 41% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of RETIN-A 0.025% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for RETIN-A 0.025% CREAM, manufactured by Bausch Health US LLC, is $0.7904 per GM (NDC 00187516045), effective Oct 1, 2025.
How has the price of RETIN-A 0.025% CREAM changed over time?
Over the history we have for it, the NADAC for RETIN-A 0.025% CREAM has declined 85.1%. It has been tracked across 390 weekly CMS publications since Apr 18, 2018.
What are the highest and lowest recorded NADAC prices for RETIN-A 0.025% CREAM?
Since Apr 18, 2018, the NADAC for RETIN-A 0.025% CREAM has ranged from a low of $0.7179 (Feb 22, 2023) to a high of $5.3213 (Mar 6, 2019), with a median of $1.6832 per GM.
Are there cheaper alternatives to RETIN-A 0.025% CREAM?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TRETINOIN 0.025% CREAM, is $0.4684 per GM — about 41% below RETIN-A 0.025% CREAM.
Who manufactures RETIN-A 0.025% CREAM?
RETIN-A 0.025% CREAM (NDC 00187516045) is labeled by Bausch Health US LLC, and CMS classifies it as a brand product.