Product Information
KETAMINE 500 MG/5 ML VIAL is a generic product labeled by Hospira Inc., priced at $1.5436 per ML under NDC 00409205105. Its NADAC has been published 40 times since Nov 19, 2025.
FDA first approved this application on Jun 27, 1996. Its Orange Book therapeutic-equivalence code is AP.
The High Outlier badge above means this manufacturer's average price in the Ketamine Hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
100 mg/mL
Manufacturer
Hospira Inc.NDC
00409205105
Classification
Generic
Dosage Form
INJECTION, SOLUTION, CONCENTRATE
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
8/19/2026
Active Ingredients
KETAMINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA074549FDA Approved
6/27/1996
TE Code
AP
On Market Since
11/30/2004
Pharmacological Classes
Price Statistics
The NADAC for KETAMINE 500 MG/5 ML VIAL has been published 40 times since Nov 19, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.5436 per ML |
|---|---|
| All-time high | $1.5655 (May 13, 2026) |
| All-time low | $1.5436 (Jul 22, 2026) |
| 52-week high | $1.5655 |
| 52-week low | $1.5436 |
| Median price | $1.5599 |
| Average price | $1.5580 |
| Largest weekly change | -0.6% (Jun 17, 2026) |
| Weeks tracked | 40 |
| Tracking since | Nov 19, 2025 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of KETAMINE 500 MG/5 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for KETAMINE 500 MG/5 ML VIAL, manufactured by Hospira Inc., is $1.5436 per ML (NDC 00409205105), effective Aug 19, 2026.
How has the price of KETAMINE 500 MG/5 ML VIAL changed over time?
Over the history we have for it, the NADAC for KETAMINE 500 MG/5 ML VIAL has held within roughly two percent of its current level. It has been tracked across 40 weekly CMS publications since Nov 19, 2025.
What are the highest and lowest recorded NADAC prices for KETAMINE 500 MG/5 ML VIAL?
Since Nov 19, 2025, the NADAC for KETAMINE 500 MG/5 ML VIAL has ranged from a low of $1.5436 (Jul 22, 2026) to a high of $1.5655 (May 13, 2026), with a median of $1.5599 per ML.
Are there cheaper alternatives to KETAMINE 500 MG/5 ML VIAL?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as KETAMINE 500 MG/5 ML VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures KETAMINE 500 MG/5 ML VIAL?
KETAMINE 500 MG/5 ML VIAL (NDC 00409205105) is labeled by Hospira Inc., and CMS classifies it as a generic product.