Product Information
KETAMINE 500 MG/5 ML VIAL is a generic product labeled by Sagent Pharmaceuticals, priced at $1.7804 per ML under NDC 25021068405. Its NADAC has been published 46 times since Nov 19, 2025.
FDA first approved this application on Jan 24, 2023. Its Orange Book therapeutic-equivalence code is AP.
Strength
100 mg/mL
Manufacturer
Sagent PharmaceuticalsNDC
25021068405
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
9/23/2026
Active Ingredients
KETAMINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA216809FDA Approved
1/24/2023
TE Code
AP
On Market Since
7/15/2023
Pharmacological Classes
Price Statistics
The NADAC for KETAMINE 500 MG/5 ML VIAL has been published 46 times since Nov 19, 2025, and over the history we have for it it has risen 13.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.7804 per ML |
|---|---|
| All-time high | $1.7804 (Sep 30, 2026) |
| All-time low | $1.5436 (Jul 22, 2026) |
| 52-week high | $1.7804 |
| 52-week low | $1.5436 |
| Median price | $1.5599 |
| Average price | $1.5664 |
| Largest weekly change | +15.3% (Sep 23, 2026) |
| Weeks tracked | 46 |
| Tracking since | Nov 19, 2025 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Sagent Pharmaceuticals manufacturer profile
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Drug market
Ketamine Hydrochloride market comparison
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Therapeutic class
General Anesthetic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of KETAMINE 500 MG/5 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for KETAMINE 500 MG/5 ML VIAL, manufactured by Sagent Pharmaceuticals, is $1.7804 per ML (NDC 25021068405), effective Sep 30, 2026.
How has the price of KETAMINE 500 MG/5 ML VIAL changed over time?
Over the history we have for it, the NADAC for KETAMINE 500 MG/5 ML VIAL has risen 13.9%. It has been tracked across 46 weekly CMS publications since Nov 19, 2025.
What are the highest and lowest recorded NADAC prices for KETAMINE 500 MG/5 ML VIAL?
Since Nov 19, 2025, the NADAC for KETAMINE 500 MG/5 ML VIAL has ranged from a low of $1.5436 (Jul 22, 2026) to a high of $1.7804 (Sep 30, 2026), with a median of $1.5599 per ML.
Are there cheaper alternatives to KETAMINE 500 MG/5 ML VIAL?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as KETAMINE 500 MG/5 ML VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures KETAMINE 500 MG/5 ML VIAL?
KETAMINE 500 MG/5 ML VIAL (NDC 25021068405) is labeled by Sagent Pharmaceuticals, and CMS classifies it as a generic product.