Product Information

HYDROCORTISONE 2.5% CREAM is a generic product labeled by Actavis Pharma, Inc., priced at $0.1255 per GM under NDC 00472033720. Its NADAC has been published 653 times since Nov 28, 2013.

FDA first approved this application on Mar 10, 1988.

HYDROCORTISONE 2.5% CREAM

Hydrocortisone
$0.1255per GM
Discontinued

Strength

25 mg/g

NDC

00472033720

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

5/20/2026

Active Ingredients

HYDROCORTISONE

Approval Type

Generic (ANDA)

FDA Application

ANDA089682

FDA Approved

3/10/1988

On Market Since

9/30/2002

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for HYDROCORTISONE 2.5% CREAM has been published 653 times since Nov 28, 2013, and over the history we have for it it has declined 6.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1255 per GM
All-time high$0.1653 (Nov 15, 2017)
All-time low$0.1032 (Jul 17, 2024)
52-week high$0.1295
52-week low$0.1231
Median price$0.1329
Average price$0.1343
Largest weekly change+38.2% (Aug 21, 2024)
Weeks tracked653
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

0.0%

6M

+0.5%

1Y

-3.1%

3Y

-16.5%

5Y

-14.4%

All

-6.3%

Last surveyed May 27, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 38% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HYDROCORTISONE 2.5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for HYDROCORTISONE 2.5% CREAM, manufactured by Actavis Pharma, Inc., is $0.1255 per GM (NDC 00472033720), effective May 27, 2026.

How has the price of HYDROCORTISONE 2.5% CREAM changed over time?

Over the history we have for it, the NADAC for HYDROCORTISONE 2.5% CREAM has declined 6.3%. It has been tracked across 653 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for HYDROCORTISONE 2.5% CREAM?

Since Nov 28, 2013, the NADAC for HYDROCORTISONE 2.5% CREAM has ranged from a low of $0.1032 (Jul 17, 2024) to a high of $0.1653 (Nov 15, 2017), with a median of $0.1329 per GM.

Are there cheaper alternatives to HYDROCORTISONE 2.5% CREAM?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCORTISONE 2.5% CREAM, is $0.0773 per GM — about 38% below HYDROCORTISONE 2.5% CREAM.

Who manufactures HYDROCORTISONE 2.5% CREAM?

HYDROCORTISONE 2.5% CREAM (NDC 00472033720) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.