Product Information
BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB is a generic product labeled by Endo USA Inc., priced at $0.5892 per EA under NDC 00603254021. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Oct 26, 1992. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 50 mg/1; mg/1
Manufacturer
Endo USA Inc.NDC
00603254021
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ACETAMINOPHEN; BUTALBITALApproval Type
Generic (ANDA)
FDA Application
ANDA089987FDA Approved
10/26/1992
TE Code
AA
On Market Since
6/3/1999
Pharmacological Classes
Price Statistics
The NADAC for BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 132.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5892 per EA |
|---|---|
| All-time high | $1.2418 (Jun 15, 2016) |
| All-time low | $0.2537 (Nov 28, 2013) |
| 52-week high | $0.7122 |
| 52-week low | $0.5411 |
| Median price | $0.9396 |
| Average price | $0.9154 |
| Largest weekly change | +254.8% (Mar 19, 2014) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB, manufactured by Endo USA Inc., is $0.5892 per EA (NDC 00603254021), effective Aug 19, 2026.
How has the price of BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB changed over time?
Over the history we have for it, the NADAC for BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB has risen 132.2%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB?
Since Nov 28, 2013, the NADAC for BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB has ranged from a low of $0.2537 (Nov 28, 2013) to a high of $1.2418 (Jun 15, 2016), with a median of $0.9396 per EA.
Are there cheaper alternatives to BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB?
BUTALBITAL-ACETAMINOPHEN 50-325 MG TAB (NDC 00603254021) is labeled by Endo USA Inc., and CMS classifies it as a generic product.