Product Information
DIPHENHYDRAMINE 50 MG/ML VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $0.9399 per ML under NDC 00641628225. Its NADAC has been published 77 times since Jan 8, 2025.
Strength
50 mg/mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00641628225
Classification
Generic
Dosage Form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS
Last Updated
6/17/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA080817On Market Since
11/27/1972
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has been published 77 times since Jan 8, 2025, and over the history we have for it it has risen 6.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.9399 per ML |
|---|---|
| All-time high | $0.9459 (Mar 11, 2026) |
| All-time low | $0.8837 (Jan 8, 2025) |
| 52-week high | $0.9459 |
| 52-week low | $0.8905 |
| Median price | $0.9212 |
| Average price | $0.9209 |
| Largest weekly change | +3.0% (Dec 17, 2025) |
| Weeks tracked | 77 |
| Tracking since | Jan 8, 2025 |
Generic Alternatives
The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 16% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 50 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 50 MG/ML VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $0.9399 per ML (NDC 00641628225), effective Jun 24, 2026.
How has the price of DIPHENHYDRAMINE 50 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has risen 6.4%. It has been tracked across 77 weekly CMS publications since Jan 8, 2025.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 50 MG/ML VIAL?
Since Jan 8, 2025, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has ranged from a low of $0.8837 (Jan 8, 2025) to a high of $0.9459 (Mar 11, 2026), with a median of $0.9212 per ML.
Are there cheaper alternatives to DIPHENHYDRAMINE 50 MG/ML VIAL?
Yes. 2 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, DIPHENHYDRAMINE 500 MG/10 ML VL, is $0.7900 per ML — about 16% below DIPHENHYDRAMINE 50 MG/ML VIAL.
Who manufactures DIPHENHYDRAMINE 50 MG/ML VIAL?
DIPHENHYDRAMINE 50 MG/ML VIAL (NDC 00641628225) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.
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