Product Information
DESONIDE 0.05% CREAM is a generic product labeled by Cosette Pharmaceuticals, Inc., priced at $0.3025 per GM under NDC 00713066115. Its NADAC has been published 572 times since Sep 9, 2015.
FDA first approved this application on Sep 28, 1992. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Cosette Pharmaceuticals, Inc.NDC
00713066115
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
DESONIDEApproval Type
Generic (ANDA)
FDA Application
ANDA074027FDA Approved
9/28/1992
TE Code
AB
On Market Since
8/19/2016
Pharmacological Classes
Price Statistics
The NADAC for DESONIDE 0.05% CREAM has been published 572 times since Sep 9, 2015, and over the history we have for it it has declined 91.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3025 per GM |
|---|---|
| All-time high | $3.5746 (Feb 10, 2016) |
| All-time low | $0.2562 (Jun 17, 2026) |
| 52-week high | $0.4448 |
| 52-week low | $0.2562 |
| Median price | $1.0808 |
| Average price | $1.3256 |
| Largest weekly change | +57.9% (Aug 21, 2024) |
| Weeks tracked | 572 |
| Tracking since | Sep 9, 2015 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 34% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DESONIDE 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% CREAM, manufactured by Cosette Pharmaceuticals, Inc., is $0.3025 per GM (NDC 00713066115), effective Aug 19, 2026.
How has the price of DESONIDE 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for DESONIDE 0.05% CREAM has declined 91.4%. It has been tracked across 572 weekly CMS publications since Sep 9, 2015.
What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% CREAM?
Since Sep 9, 2015, the NADAC for DESONIDE 0.05% CREAM has ranged from a low of $0.2562 (Jun 17, 2026) to a high of $3.5746 (Feb 10, 2016), with a median of $1.0808 per GM.
Are there cheaper alternatives to DESONIDE 0.05% CREAM?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DESONIDE 0.05% CREAM, is $0.1996 per GM — about 34% below DESONIDE 0.05% CREAM.
Who manufactures DESONIDE 0.05% CREAM?
DESONIDE 0.05% CREAM (NDC 00713066115) is labeled by Cosette Pharmaceuticals, Inc., and CMS classifies it as a generic product.