Product Information
DESONIDE 0.05% CREAM is a generic product labeled by Cosette Pharmaceuticals, Inc., priced at $0.3056 per GM under NDC 00713066115. Its NADAC has been published 578 times since Sep 9, 2015.
FDA first approved this application on Sep 28, 1992. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Cosette Pharmaceuticals, Inc.NDC
00713066115
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
DESONIDEApproval Type
Generic (ANDA)
FDA Application
ANDA074027FDA Approved
9/28/1992
TE Code
AB
On Market Since
8/19/2016
Pharmacological Classes
Price Statistics
The NADAC for DESONIDE 0.05% CREAM has been published 578 times since Sep 9, 2015, and over the history we have for it it has declined 91.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3056 per GM |
|---|---|
| All-time high | $3.5746 (Feb 10, 2016) |
| All-time low | $0.2562 (Jun 17, 2026) |
| 52-week high | $0.4064 |
| 52-week low | $0.2562 |
| Median price | $1.0593 |
| Average price | $1.3150 |
| Largest weekly change | +57.9% (Aug 21, 2024) |
| Weeks tracked | 578 |
| Tracking since | Sep 9, 2015 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 35% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Cosette Pharmaceuticals, Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Desonide market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Corticosteroid class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DESONIDE 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% CREAM, manufactured by Cosette Pharmaceuticals, Inc., is $0.3056 per GM (NDC 00713066115), effective Sep 30, 2026.
How has the price of DESONIDE 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for DESONIDE 0.05% CREAM has declined 91.3%. It has been tracked across 578 weekly CMS publications since Sep 9, 2015.
What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% CREAM?
Since Sep 9, 2015, the NADAC for DESONIDE 0.05% CREAM has ranged from a low of $0.2562 (Jun 17, 2026) to a high of $3.5746 (Feb 10, 2016), with a median of $1.0593 per GM.
Are there cheaper alternatives to DESONIDE 0.05% CREAM?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DESONIDE 0.05% CREAM, is $0.1974 per GM — about 35% below DESONIDE 0.05% CREAM.
Who manufactures DESONIDE 0.05% CREAM?
DESONIDE 0.05% CREAM (NDC 00713066115) is labeled by Cosette Pharmaceuticals, Inc., and CMS classifies it as a generic product.