Product Information
DESONIDE 0.05% CREAM is a generic product labeled by NorthStar Rx LLC, priced at $0.1996 per GM under NDC 16714072902. Its NADAC has been published 454 times since Dec 13, 2017.
FDA first approved this application on Jun 30, 1992. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
NorthStar Rx LLCNDC
16714072902
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
DESONIDEApproval Type
Generic (ANDA)
FDA Application
ANDA073548FDA Approved
6/30/1992
TE Code
AB
On Market Since
6/30/1992
Pharmacological Classes
Price Statistics
The NADAC for DESONIDE 0.05% CREAM has been published 454 times since Dec 13, 2017, and over the history we have for it it has declined 89.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1996 per GM |
|---|---|
| All-time high | $1.9821 (Dec 13, 2017) |
| All-time low | $0.1887 (Jun 17, 2026) |
| 52-week high | $0.2413 |
| 52-week low | $0.1887 |
| Median price | $0.5552 |
| Average price | $0.7169 |
| Largest weekly change | +50.8% (Feb 22, 2023) |
| Weeks tracked | 454 |
| Tracking since | Dec 13, 2017 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DESONIDE 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% CREAM, manufactured by NorthStar Rx LLC, is $0.1996 per GM (NDC 16714072902), effective Aug 19, 2026.
How has the price of DESONIDE 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for DESONIDE 0.05% CREAM has declined 89.9%. It has been tracked across 454 weekly CMS publications since Dec 13, 2017.
What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% CREAM?
Since Dec 13, 2017, the NADAC for DESONIDE 0.05% CREAM has ranged from a low of $0.1887 (Jun 17, 2026) to a high of $1.9821 (Dec 13, 2017), with a median of $0.5552 per GM.
Are there cheaper alternatives to DESONIDE 0.05% CREAM?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DESONIDE 0.05% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures DESONIDE 0.05% CREAM?
DESONIDE 0.05% CREAM (NDC 16714072902) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.