Product Information

DESONIDE 0.05% CREAM is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $0.1996 per GM under NDC 51672128003. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Jun 30, 1992. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DESONIDE 0.05% CREAM

Desonide
$0.1996per GM

Strength

.5 mg/g

NDC

51672128003

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

DESONIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA073548

FDA Approved

6/30/1992

TE Code

AB

On Market Since

6/30/1992

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for DESONIDE 0.05% CREAM has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 95.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1996 per GM
All-time high$4.1692 (Jan 15, 2014)
All-time low$0.1887 (Jun 17, 2026)
52-week high$0.2413
52-week low$0.1887
Median price$1.0597
Average price$1.4855
Largest weekly change+50.8% (Feb 22, 2023)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+3.7%

1M

+3.7%

3M

-0.1%

6M

+0.1%

1Y

-17.3%

3Y

-50.5%

5Y

-72.6%

All

-95.1%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DESONIDE 0.05% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% CREAM, manufactured by Sun Pharmaceutical Industries Inc., is $0.1996 per GM (NDC 51672128003), effective Aug 19, 2026.

How has the price of DESONIDE 0.05% CREAM changed over time?

Over the history we have for it, the NADAC for DESONIDE 0.05% CREAM has declined 95.1%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% CREAM?

Since Nov 28, 2013, the NADAC for DESONIDE 0.05% CREAM has ranged from a low of $0.1887 (Jun 17, 2026) to a high of $4.1692 (Jan 15, 2014), with a median of $1.0597 per GM.

Are there cheaper alternatives to DESONIDE 0.05% CREAM?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DESONIDE 0.05% CREAM in a comparable dosage form, but none are currently priced below it.

Who manufactures DESONIDE 0.05% CREAM?

DESONIDE 0.05% CREAM (NDC 51672128003) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.