Product Information
DESONIDE 0.05% CREAM is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $0.1974 per GM under NDC 51672128003. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Jun 30, 1992. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Sun Pharmaceutical Industries Inc.NDC
51672128003
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
DESONIDEApproval Type
Generic (ANDA)
FDA Application
ANDA073548FDA Approved
6/30/1992
TE Code
AB
On Market Since
6/30/1992
Pharmacological Classes
Price Statistics
The NADAC for DESONIDE 0.05% CREAM has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 95.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1974 per GM |
|---|---|
| All-time high | $4.1692 (Jan 15, 2014) |
| All-time low | $0.1887 (Jun 17, 2026) |
| 52-week high | $0.2320 |
| 52-week low | $0.1887 |
| Median price | $1.0597 |
| Average price | $1.4740 |
| Largest weekly change | +50.8% (Feb 22, 2023) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Sun Pharmaceutical Industries Inc. manufacturer profile
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Drug market
Desonide market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DESONIDE 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% CREAM, manufactured by Sun Pharmaceutical Industries Inc., is $0.1974 per GM (NDC 51672128003), effective Sep 30, 2026.
How has the price of DESONIDE 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for DESONIDE 0.05% CREAM has declined 95.1%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% CREAM?
Since Nov 28, 2013, the NADAC for DESONIDE 0.05% CREAM has ranged from a low of $0.1887 (Jun 17, 2026) to a high of $4.1692 (Jan 15, 2014), with a median of $1.0597 per GM.
Are there cheaper alternatives to DESONIDE 0.05% CREAM?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DESONIDE 0.05% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures DESONIDE 0.05% CREAM?
DESONIDE 0.05% CREAM (NDC 51672128003) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.