Product Information

DESONIDE 0.05% CREAM is a generic product labeled by Cosette Pharmaceuticals, Inc., priced at $0.1996 per GM under NDC 00713066160. Its NADAC has been published 572 times since Sep 9, 2015.

FDA first approved this application on Sep 28, 1992. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DESONIDE 0.05% CREAM

Desonide
$0.1996per GM

Strength

.5 mg/g

NDC

00713066160

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

DESONIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA074027

FDA Approved

9/28/1992

TE Code

AB

On Market Since

8/19/2016

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for DESONIDE 0.05% CREAM has been published 572 times since Sep 9, 2015, and over the history we have for it it has declined 93.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1996 per GM
All-time high$3.2516 (Dec 16, 2015)
All-time low$0.1887 (Jun 17, 2026)
52-week high$0.2413
52-week low$0.1887
Median price$0.9051
Average price$1.1228
Largest weekly change+50.8% (Feb 22, 2023)
Weeks tracked572
Tracking sinceSep 9, 2015

Price History

1W

+3.7%

1M

+3.7%

3M

-0.1%

6M

+0.1%

1Y

-17.3%

3Y

-50.5%

5Y

-72.6%

All

-93.6%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DESONIDE 0.05% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for DESONIDE 0.05% CREAM, manufactured by Cosette Pharmaceuticals, Inc., is $0.1996 per GM (NDC 00713066160), effective Aug 19, 2026.

How has the price of DESONIDE 0.05% CREAM changed over time?

Over the history we have for it, the NADAC for DESONIDE 0.05% CREAM has declined 93.6%. It has been tracked across 572 weekly CMS publications since Sep 9, 2015.

What are the highest and lowest recorded NADAC prices for DESONIDE 0.05% CREAM?

Since Sep 9, 2015, the NADAC for DESONIDE 0.05% CREAM has ranged from a low of $0.1887 (Jun 17, 2026) to a high of $3.2516 (Dec 16, 2015), with a median of $0.9051 per GM.

Are there cheaper alternatives to DESONIDE 0.05% CREAM?

5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DESONIDE 0.05% CREAM in a comparable dosage form, but none are currently priced below it.

Who manufactures DESONIDE 0.05% CREAM?

DESONIDE 0.05% CREAM (NDC 00713066160) is labeled by Cosette Pharmaceuticals, Inc., and CMS classifies it as a generic product.