Product Information

BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $2.8820 per ML under NDC 00832142505. Its NADAC has been published 162 times since May 24, 2023.

BRIMONIDINE-TIMOLOL 0.2%-0.5%

Brimonidine Tartrate and Timolol Maleate
$2.8820per ML

Strength

2; 5 mg/mL; mg/mL

NDC

00832142505

Classification

Generic

Dosage Form

SOLUTION/ DROPS

Route

OPHTHALMIC

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA215598

On Market Since

12/15/2022

Pharmacological Classes

Adrenergic alpha-Agonists
Adrenergic beta-Antagonists
alpha-Adrenergic Agonist
beta-Adrenergic Blocker

Price Statistics

The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 162 times since May 24, 2023, and over the history we have for it it has declined 82.9%. The table below summarizes its recorded NADAC range and movement.

Current price$2.8820 per ML
All-time high$17.4215 (Aug 16, 2023)
All-time low$2.8820 (Jun 17, 2026)
52-week high$5.4857
52-week low$2.8820
Median price$6.6603
Average price$8.6457
Largest weekly change-37.2% (Jul 17, 2024)
Weeks tracked162
Tracking sinceMay 24, 2023

Price History

1W

0.0%

1M

-7.9%

3M

-10.9%

6M

-22.5%

1Y

-47.5%

3Y

-83.0%

5Y

N/A

All

-82.9%

Generic Alternatives

The matcher finds 8 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 8 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 27% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?

The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Upsher-Smith Laboratories LLC, is $2.8820 per ML (NDC 00832142505), effective Jun 24, 2026.

How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?

Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 82.9%. It has been tracked across 162 weekly CMS publications since May 24, 2023.

What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?

Since May 24, 2023, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $2.8820 (Jun 17, 2026) to a high of $17.4215 (Aug 16, 2023), with a median of $6.6603 per ML.

Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?

Yes. 8 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, BRIMONIDINE-TIMOLOL 0.2%-0.5%, is $2.1018 per ML — about 27% below BRIMONIDINE-TIMOLOL 0.2%-0.5%.

Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?

BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 00832142505) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.