Product Information

CHLORTHALIDONE 25 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0840 per EA under NDC 00904690004. Its NADAC has been published 361 times since Sep 25, 2019.

FDA first approved this application on Jul 21, 1986. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The Low Outlier badge above means this manufacturer's average price in the Chlorthalidone market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

CHLORTHALIDONE 25 MG TABLET

Chlorthalidone
$0.0840per EA
Low Outlier

Strength

25 mg/1

NDC

00904690004

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

CHLORTHALIDONE

Approval Type

Generic (ANDA)

FDA Application

ANDA089286

FDA Approved

7/21/1986

TE Code

AB

On Market Since

2/12/2016

Pharmacological Classes

Increased Diuresis
Thiazide-like Diuretic

Price Statistics

The NADAC for CHLORTHALIDONE 25 MG TABLET has been published 361 times since Sep 25, 2019, and over the history we have for it it has declined 80.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0840 per EA
All-time high$0.4602 (Jan 15, 2020)
All-time low$0.0703 (Jul 17, 2024)
52-week high$0.0901
52-week low$0.0833
Median price$0.1099
Average price$0.1602
Largest weekly change+30.9% (Aug 21, 2024)
Weeks tracked361
Tracking sinceSep 25, 2019

Price History

1W

-1.0%

1M

-1.0%

3M

-5.5%

6M

+0.8%

1Y

-3.2%

3Y

-14.0%

5Y

-50.7%

All

-80.1%

Generic Alternatives

The matcher finds 14 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CHLORTHALIDONE 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for CHLORTHALIDONE 25 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0840 per EA (NDC 00904690004), effective Aug 19, 2026.

How has the price of CHLORTHALIDONE 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for CHLORTHALIDONE 25 MG TABLET has declined 80.1%. It has been tracked across 361 weekly CMS publications since Sep 25, 2019.

What are the highest and lowest recorded NADAC prices for CHLORTHALIDONE 25 MG TABLET?

Since Sep 25, 2019, the NADAC for CHLORTHALIDONE 25 MG TABLET has ranged from a low of $0.0703 (Jul 17, 2024) to a high of $0.4602 (Jan 15, 2020), with a median of $0.1099 per EA.

Are there cheaper alternatives to CHLORTHALIDONE 25 MG TABLET?

14 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CHLORTHALIDONE 25 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures CHLORTHALIDONE 25 MG TABLET?

CHLORTHALIDONE 25 MG TABLET (NDC 00904690004) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.