Product Information
METOLAZONE 5 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.2643 per EA under NDC 00904732961. Its NADAC has been published 142 times since Dec 20, 2023.
FDA first approved this application on Mar 30, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904732961
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METOLAZONEApproval Type
Generic (ANDA)
FDA Application
ANDA213827FDA Approved
3/30/2021
TE Code
AB
On Market Since
8/30/2023
Pharmacological Classes
Price Statistics
The NADAC for METOLAZONE 5 MG TABLET has been published 142 times since Dec 20, 2023, and over the history we have for it it has declined 25.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2643 per EA |
|---|---|
| All-time high | $0.3729 (Aug 14, 2024) |
| All-time low | $0.2163 (Apr 17, 2024) |
| 52-week high | $0.3323 |
| 52-week low | $0.2643 |
| Median price | $0.2905 |
| Average price | $0.2871 |
| Largest weekly change | +52.5% (Jul 17, 2024) |
| Weeks tracked | 142 |
| Tracking since | Dec 20, 2023 |
1W
N/A
1M
N/A
3M
-10.2%
6M
-13.9%
1Y
-6.9%
3Y
N/A
5Y
N/A
All
-25.2%
Last surveyed Sep 2, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 10% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Major Pharmaceuticals manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Metolazone market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Thiazide-like Diuretic class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METOLAZONE 5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METOLAZONE 5 MG TABLET, manufactured by Major Pharmaceuticals, is $0.2643 per EA (NDC 00904732961), effective Sep 2, 2026.
How has the price of METOLAZONE 5 MG TABLET changed over time?
Over the history we have for it, the NADAC for METOLAZONE 5 MG TABLET has declined 25.2%. It has been tracked across 142 weekly CMS publications since Dec 20, 2023.
What are the highest and lowest recorded NADAC prices for METOLAZONE 5 MG TABLET?
Since Dec 20, 2023, the NADAC for METOLAZONE 5 MG TABLET has ranged from a low of $0.2163 (Apr 17, 2024) to a high of $0.3729 (Aug 14, 2024), with a median of $0.2905 per EA.
Are there cheaper alternatives to METOLAZONE 5 MG TABLET?
Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METOLAZONE 5 MG TABLET, is $0.2392 per EA — about 10% below METOLAZONE 5 MG TABLET.
Who manufactures METOLAZONE 5 MG TABLET?
METOLAZONE 5 MG TABLET (NDC 00904732961) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.