Product Information

METOLAZONE 5 MG TABLET is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.2643 per EA under NDC 58657074101. Its NADAC has been published 93 times since Nov 13, 2024.

FDA first approved this application on Mar 30, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METOLAZONE 5 MG TABLET

Metolazone
$0.2643per EA

Strength

5 mg/1

NDC

58657074101

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METOLAZONE

Approval Type

Generic (ANDA)

FDA Application

ANDA213827

FDA Approved

3/30/2021

TE Code

AB

On Market Since

6/15/2024

Pharmacological Classes

Increased Diuresis
Thiazide-like Diuretic

Price Statistics

The NADAC for METOLAZONE 5 MG TABLET has been published 93 times since Nov 13, 2024, and over the history we have for it it has declined 2.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2643 per EA
All-time high$0.3323 (Feb 11, 2026)
All-time low$0.2196 (Jan 22, 2025)
52-week high$0.3323
52-week low$0.2643
Median price$0.2910
Average price$0.2843
Largest weekly change-18.5% (Nov 20, 2024)
Weeks tracked93
Tracking sinceNov 13, 2024

Price History

1W

-1.7%

1M

-1.7%

3M

-9.2%

6M

-18.0%

1Y

-5.7%

3Y

N/A

5Y

N/A

All

-2.5%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METOLAZONE 5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for METOLAZONE 5 MG TABLET, manufactured by Method Pharmaceuticals LLC, is $0.2643 per EA (NDC 58657074101), effective Aug 19, 2026.

How has the price of METOLAZONE 5 MG TABLET changed over time?

Over the history we have for it, the NADAC for METOLAZONE 5 MG TABLET has declined 2.5%. It has been tracked across 93 weekly CMS publications since Nov 13, 2024.

What are the highest and lowest recorded NADAC prices for METOLAZONE 5 MG TABLET?

Since Nov 13, 2024, the NADAC for METOLAZONE 5 MG TABLET has ranged from a low of $0.2196 (Jan 22, 2025) to a high of $0.3323 (Feb 11, 2026), with a median of $0.2910 per EA.

Are there cheaper alternatives to METOLAZONE 5 MG TABLET?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METOLAZONE 5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures METOLAZONE 5 MG TABLET?

METOLAZONE 5 MG TABLET (NDC 58657074101) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.