Product Information
AMITRIPTYLINE HCL 50 MG TAB is a generic product labeled by Major Pharmaceuticals, priced at $0.0957 per EA under NDC 00904741161. Its NADAC has been published 106 times since Jun 19, 2024.
The Low Outlier badge above means this manufacturer's average price in the Amitriptyline Hydrochloride market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904741161
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
AMITRIPTYLINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA217411On Market Since
3/8/2024
Pharmacological Classes
Price Statistics
The NADAC for AMITRIPTYLINE HCL 50 MG TAB has been published 106 times since Jun 19, 2024, and over the history we have for it it has risen 2.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0957 per EA |
|---|---|
| All-time high | $0.1019 (Jun 10, 2026) |
| All-time low | $0.0677 (Nov 20, 2024) |
| 52-week high | $0.1019 |
| 52-week low | $0.0889 |
| Median price | $0.0926 |
| Average price | $0.0887 |
| Largest weekly change | +40.1% (Aug 21, 2024) |
| Weeks tracked | 106 |
| Tracking since | Jun 19, 2024 |
Generic Alternatives
The matcher finds 11 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 10 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of AMITRIPTYLINE HCL 50 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for AMITRIPTYLINE HCL 50 MG TAB, manufactured by Major Pharmaceuticals, is $0.0957 per EA (NDC 00904741161), effective Jun 24, 2026.
How has the price of AMITRIPTYLINE HCL 50 MG TAB changed over time?
Over the history we have for it, the NADAC for AMITRIPTYLINE HCL 50 MG TAB has risen 2.4%. It has been tracked across 106 weekly CMS publications since Jun 19, 2024.
What are the highest and lowest recorded NADAC prices for AMITRIPTYLINE HCL 50 MG TAB?
Since Jun 19, 2024, the NADAC for AMITRIPTYLINE HCL 50 MG TAB has ranged from a low of $0.0677 (Nov 20, 2024) to a high of $0.1019 (Jun 10, 2026), with a median of $0.0926 per EA.
Are there cheaper alternatives to AMITRIPTYLINE HCL 50 MG TAB?
11 NADAC-published products share the same active ingredient, strength, and dosage form as AMITRIPTYLINE HCL 50 MG TAB, but none are currently priced below it.
Who manufactures AMITRIPTYLINE HCL 50 MG TAB?
AMITRIPTYLINE HCL 50 MG TAB (NDC 00904741161) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.
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