Product Information
CARBIDOPA-LEVODOPA 25-250 TAB is a generic product labeled by Major Pharmaceuticals, priced at $0.1094 per EA under NDC 00904754961. Its NADAC has been published 44 times since Oct 22, 2025.
FDA first approved this application on Aug 28, 1992. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25; 250 mg/1; mg/1
Manufacturer
Major PharmaceuticalsNDC
00904754961
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
CARBIDOPA; LEVODOPAApproval Type
Generic (ANDA)
FDA Application
ANDA073607FDA Approved
8/28/1992
TE Code
AB
On Market Since
4/28/2025
Pharmacological Classes
Price Statistics
The NADAC for CARBIDOPA-LEVODOPA 25-250 TAB has been published 44 times since Oct 22, 2025, and over the history we have for it it has declined 12.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1094 per EA |
|---|---|
| All-time high | $0.1295 (Dec 10, 2025) |
| All-time low | $0.1085 (Jul 22, 2026) |
| 52-week high | $0.1295 |
| 52-week low | $0.1085 |
| Median price | $0.1131 |
| Average price | $0.1171 |
| Largest weekly change | -5.8% (Feb 18, 2026) |
| Weeks tracked | 44 |
| Tracking since | Oct 22, 2025 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CARBIDOPA-LEVODOPA 25-250 TAB?
The current National Average Drug Acquisition Cost (NADAC) for CARBIDOPA-LEVODOPA 25-250 TAB, manufactured by Major Pharmaceuticals, is $0.1094 per EA (NDC 00904754961), effective Aug 19, 2026.
How has the price of CARBIDOPA-LEVODOPA 25-250 TAB changed over time?
Over the history we have for it, the NADAC for CARBIDOPA-LEVODOPA 25-250 TAB has declined 12.9%. It has been tracked across 44 weekly CMS publications since Oct 22, 2025.
What are the highest and lowest recorded NADAC prices for CARBIDOPA-LEVODOPA 25-250 TAB?
Since Oct 22, 2025, the NADAC for CARBIDOPA-LEVODOPA 25-250 TAB has ranged from a low of $0.1085 (Jul 22, 2026) to a high of $0.1295 (Dec 10, 2025), with a median of $0.1131 per EA.
Are there cheaper alternatives to CARBIDOPA-LEVODOPA 25-250 TAB?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CARBIDOPA-LEVODOPA 25-250 TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures CARBIDOPA-LEVODOPA 25-250 TAB?
CARBIDOPA-LEVODOPA 25-250 TAB (NDC 00904754961) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.