Product Information
ESTRADIOL 0.1% (1 MG) GEL PKT is a generic product labeled by Trigen Laboratories, LLC, priced at $1.1272 per GM under NDC 13811009332. Its NADAC has been published 183 times since Feb 22, 2023.
FDA first approved this application on Jun 4, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1 mg/g
Manufacturer
Trigen Laboratories, LLCNDC
13811009332
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA022038FDA Approved
6/4/2007
TE Code
AB
On Market Since
10/10/2022
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.1% (1 MG) GEL PKT has been published 183 times since Feb 22, 2023, and over the history we have for it it has declined 67.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.1272 per GM |
|---|---|
| All-time high | $4.0103 (Oct 11, 2023) |
| All-time low | $1.1272 (Aug 19, 2026) |
| 52-week high | $2.0960 |
| 52-week low | $1.1272 |
| Median price | $2.0671 |
| Average price | $2.4522 |
| Largest weekly change | -55.7% (Apr 17, 2024) |
| Weeks tracked | 183 |
| Tracking since | Feb 22, 2023 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.1% (1 MG) GEL PKT?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (1 MG) GEL PKT, manufactured by Trigen Laboratories, LLC, is $1.1272 per GM (NDC 13811009332), effective Aug 19, 2026.
How has the price of ESTRADIOL 0.1% (1 MG) GEL PKT changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.1% (1 MG) GEL PKT has declined 67.4%. It has been tracked across 183 weekly CMS publications since Feb 22, 2023.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (1 MG) GEL PKT?
Since Feb 22, 2023, the NADAC for ESTRADIOL 0.1% (1 MG) GEL PKT has ranged from a low of $1.1272 (Aug 19, 2026) to a high of $4.0103 (Oct 11, 2023), with a median of $2.0671 per GM.
Are there cheaper alternatives to ESTRADIOL 0.1% (1 MG) GEL PKT?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.1% (1 MG) GEL PKT in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL 0.1% (1 MG) GEL PKT?
ESTRADIOL 0.1% (1 MG) GEL PKT (NDC 13811009332) is labeled by Trigen Laboratories, LLC, and CMS classifies it as a generic product.