Product Information
CLOBETASOL 0.05% SOLUTION is a generic product labeled by Encube Ethicals, Inc., priced at $0.2504 per ML under NDC 21922006122. Its NADAC has been published 104 times since Jul 3, 2024.
Strength
.5 mg/mL
Manufacturer
Encube Ethicals, Inc.NDC
21922006122
Classification
Generic
Dosage Form
SOLUTION
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA076977On Market Since
6/10/2024
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL 0.05% SOLUTION has been published 104 times since Jul 3, 2024, and over the history we have for it it has declined 36.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2504 per ML |
|---|---|
| All-time high | $0.4714 (Nov 13, 2024) |
| All-time low | $0.2504 (Jun 17, 2026) |
| 52-week high | $0.3044 |
| 52-week low | $0.2504 |
| Median price | $0.2994 |
| Average price | $0.3184 |
| Largest weekly change | +36.0% (Aug 21, 2024) |
| Weeks tracked | 104 |
| Tracking since | Jul 3, 2024 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 53% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of CLOBETASOL 0.05% SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% SOLUTION, manufactured by Encube Ethicals, Inc., is $0.2504 per ML (NDC 21922006122), effective Jun 24, 2026.
How has the price of CLOBETASOL 0.05% SOLUTION changed over time?
Over the history we have for it, the NADAC for CLOBETASOL 0.05% SOLUTION has declined 36.6%. It has been tracked across 104 weekly CMS publications since Jul 3, 2024.
What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% SOLUTION?
Since Jul 3, 2024, the NADAC for CLOBETASOL 0.05% SOLUTION has ranged from a low of $0.2504 (Jun 17, 2026) to a high of $0.4714 (Nov 13, 2024), with a median of $0.2994 per ML.
Are there cheaper alternatives to CLOBETASOL 0.05% SOLUTION?
Yes. 5 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, CLOBETASOL 0.05% SOLUTION, is $0.1172 per ML — about 53% below CLOBETASOL 0.05% SOLUTION.
Who manufactures CLOBETASOL 0.05% SOLUTION?
CLOBETASOL 0.05% SOLUTION (NDC 21922006122) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.
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