Product Information
BUPROPION HCL XL 150 MG TABLET is a generic product labeled by Epic Pharma LLC, priced at $0.0787 per EA under NDC 42806034805. Its NADAC has been published 364 times since Sep 4, 2019.
FDA first approved this application on Jun 30, 2017. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
150 mg/1
Manufacturer
Epic Pharma LLCNDC
42806034805
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA207224FDA Approved
6/30/2017
TE Code
AB3
On Market Since
10/1/2017
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL XL 150 MG TABLET has been published 364 times since Sep 4, 2019, and over the history we have for it it has declined 73.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0787 per EA |
|---|---|
| All-time high | $0.2963 (Sep 11, 2019) |
| All-time low | $0.0745 (Nov 20, 2024) |
| 52-week high | $0.0996 |
| 52-week low | $0.0770 |
| Median price | $0.1111 |
| Average price | $0.1308 |
| Largest weekly change | -30.3% (Nov 20, 2024) |
| Weeks tracked | 364 |
| Tracking since | Sep 4, 2019 |
1W
N/A
1M
N/A
3M
+1.1%
6M
-0.6%
1Y
-21.0%
3Y
-22.3%
5Y
-50.5%
All
-73.4%
Last surveyed Aug 19, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Epic Pharma LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Bupropion Hydrochloride market comparison
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Therapeutic class
Aminoketone class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUPROPION HCL XL 150 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 150 MG TABLET, manufactured by Epic Pharma LLC, is $0.0787 per EA (NDC 42806034805), effective Aug 19, 2026.
How has the price of BUPROPION HCL XL 150 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL XL 150 MG TABLET has declined 73.4%. It has been tracked across 364 weekly CMS publications since Sep 4, 2019.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 150 MG TABLET?
Since Sep 4, 2019, the NADAC for BUPROPION HCL XL 150 MG TABLET has ranged from a low of $0.0745 (Nov 20, 2024) to a high of $0.2963 (Sep 11, 2019), with a median of $0.1111 per EA.
Are there cheaper alternatives to BUPROPION HCL XL 150 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUPROPION HCL XL 150 MG TABLET, is $0.0785 per EA — about 0% below BUPROPION HCL XL 150 MG TABLET.
Who manufactures BUPROPION HCL XL 150 MG TABLET?
BUPROPION HCL XL 150 MG TABLET (NDC 42806034805) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.