Product Information
BUPROPION HCL XL 150 MG TABLET is a generic product labeled by AvPAK, priced at $0.0787 per EA under NDC 50268013313. Its NADAC has been published 49 times since Sep 17, 2025.
FDA first approved this application on Apr 6, 2017. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
150 mg/1
Manufacturer
AvPAKNDC
50268013313
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA090693FDA Approved
4/6/2017
TE Code
AB3
On Market Since
3/5/2025
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL XL 150 MG TABLET has been published 49 times since Sep 17, 2025, and over the history we have for it it has declined 21.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0787 per EA |
|---|---|
| All-time high | $0.0996 (Oct 15, 2025) |
| All-time low | $0.0770 (Apr 22, 2026) |
| 52-week high | $0.0996 |
| 52-week low | $0.0770 |
| Median price | $0.0792 |
| Average price | $0.0848 |
| Largest weekly change | -8.4% (Feb 18, 2026) |
| Weeks tracked | 49 |
| Tracking since | Sep 17, 2025 |
Generic Alternatives
The matcher finds 10 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUPROPION HCL XL 150 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 150 MG TABLET, manufactured by AvPAK, is $0.0787 per EA (NDC 50268013313), effective Aug 19, 2026.
How has the price of BUPROPION HCL XL 150 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL XL 150 MG TABLET has declined 21.0%. It has been tracked across 49 weekly CMS publications since Sep 17, 2025.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 150 MG TABLET?
Since Sep 17, 2025, the NADAC for BUPROPION HCL XL 150 MG TABLET has ranged from a low of $0.0770 (Apr 22, 2026) to a high of $0.0996 (Oct 15, 2025), with a median of $0.0792 per EA.
Are there cheaper alternatives to BUPROPION HCL XL 150 MG TABLET?
10 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL XL 150 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPROPION HCL XL 150 MG TABLET?
BUPROPION HCL XL 150 MG TABLET (NDC 50268013313) is labeled by AvPAK, and CMS classifies it as a generic product.