Product Information

BUPROPION HCL 100 MG TABLET is a generic product labeled by Aurobindo Pharma Limited, priced at $0.1151 per EA under NDC 59651087501. Its NADAC has been published 78 times since Feb 26, 2025.

FDA first approved this application on Apr 17, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL 100 MG TABLET

BUPROPION HYDROCHLORIDE
$0.1151per EA

Strength

100 mg/1

NDC

59651087501

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA075491

FDA Approved

4/17/2000

TE Code

AB

On Market Since

4/25/2024

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL 100 MG TABLET has been published 78 times since Feb 26, 2025, and over the history we have for it it has declined 2.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1151 per EA
All-time high$0.1273 (May 14, 2025)
All-time low$0.1139 (Jul 22, 2026)
52-week high$0.1268
52-week low$0.1139
Median price$0.1216
Average price$0.1219
Largest weekly change+6.3% (Mar 19, 2025)
Weeks tracked78
Tracking sinceFeb 26, 2025

Price History

1W

+1.1%

1M

-0.9%

3M

-1.6%

6M

-5.5%

1Y

-9.2%

3Y

N/A

5Y

N/A

All

-2.8%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 40% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 40%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of BUPROPION HCL 100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL 100 MG TABLET, manufactured by Aurobindo Pharma Limited, is $0.1151 per EA (NDC 59651087501), effective Aug 19, 2026.

How has the price of BUPROPION HCL 100 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL 100 MG TABLET has declined 2.8%. It has been tracked across 78 weekly CMS publications since Feb 26, 2025.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL 100 MG TABLET?

Since Feb 26, 2025, the NADAC for BUPROPION HCL 100 MG TABLET has ranged from a low of $0.1139 (Jul 22, 2026) to a high of $0.1273 (May 14, 2025), with a median of $0.1216 per EA.

Are there cheaper alternatives to BUPROPION HCL 100 MG TABLET?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUPROPION HCL SR 100 MG TABLET, is $0.0687 per EA — about 40% below BUPROPION HCL 100 MG TABLET.

Who manufactures BUPROPION HCL 100 MG TABLET?

BUPROPION HCL 100 MG TABLET (NDC 59651087501) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.