Product Information
BUPROPION HCL 100 MG TABLET is a generic product labeled by Aurobindo Pharma Limited, priced at $0.1129 per EA under NDC 59651087501. Its NADAC has been published 84 times since Feb 26, 2025.
FDA first approved this application on Apr 17, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
Aurobindo Pharma LimitedNDC
59651087501
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075491FDA Approved
4/17/2000
TE Code
AB
On Market Since
4/25/2024
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL 100 MG TABLET has been published 84 times since Feb 26, 2025, and over the history we have for it it has declined 4.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1129 per EA |
|---|---|
| All-time high | $0.1273 (May 14, 2025) |
| All-time low | $0.1129 (Sep 23, 2026) |
| 52-week high | $0.1247 |
| 52-week low | $0.1129 |
| Median price | $0.1213 |
| Average price | $0.1213 |
| Largest weekly change | +6.3% (Mar 19, 2025) |
| Weeks tracked | 84 |
| Tracking since | Feb 26, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 39% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Aurobindo Pharma Limited manufacturer profile
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Drug market
BUPROPION HYDROCHLORIDE market comparison
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Therapeutic class
Aminoketone class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUPROPION HCL 100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL 100 MG TABLET, manufactured by Aurobindo Pharma Limited, is $0.1129 per EA (NDC 59651087501), effective Sep 30, 2026.
How has the price of BUPROPION HCL 100 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL 100 MG TABLET has declined 4.6%. It has been tracked across 84 weekly CMS publications since Feb 26, 2025.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL 100 MG TABLET?
Since Feb 26, 2025, the NADAC for BUPROPION HCL 100 MG TABLET has ranged from a low of $0.1129 (Sep 23, 2026) to a high of $0.1273 (May 14, 2025), with a median of $0.1213 per EA.
Are there cheaper alternatives to BUPROPION HCL 100 MG TABLET?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUPROPION HCL SR 100 MG TABLET, is $0.0687 per EA — about 39% below BUPROPION HCL 100 MG TABLET.
Who manufactures BUPROPION HCL 100 MG TABLET?
BUPROPION HCL 100 MG TABLET (NDC 59651087501) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.