Product Information
BUPROPION HCL XL 150 MG TABLET is a generic product labeled by Epic Pharma LLC, priced at $0.0785 per EA under NDC 42806041430. Its NADAC has been published 173 times since Jun 14, 2023.
FDA first approved this application on Jun 14, 2018. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
150 mg/1
Manufacturer
Epic Pharma LLCNDC
42806041430
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA210015FDA Approved
6/14/2018
TE Code
AB3
On Market Since
4/30/2023
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL XL 150 MG TABLET has been published 173 times since Jun 14, 2023, and over the history we have for it it has declined 20.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0785 per EA |
|---|---|
| All-time high | $0.1215 (Apr 10, 2024) |
| All-time low | $0.0745 (Nov 20, 2024) |
| 52-week high | $0.0996 |
| 52-week low | $0.0770 |
| Median price | $0.1011 |
| Average price | $0.0976 |
| Largest weekly change | -30.3% (Nov 20, 2024) |
| Weeks tracked | 173 |
| Tracking since | Jun 14, 2023 |
Generic Alternatives
The matcher finds 14 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Epic Pharma LLC manufacturer profile
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Drug market
bupropion hydrochloride market comparison
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Therapeutic class
Aminoketone class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUPROPION HCL XL 150 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 150 MG TABLET, manufactured by Epic Pharma LLC, is $0.0785 per EA (NDC 42806041430), effective Sep 30, 2026.
How has the price of BUPROPION HCL XL 150 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL XL 150 MG TABLET has declined 20.9%. It has been tracked across 173 weekly CMS publications since Jun 14, 2023.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 150 MG TABLET?
Since Jun 14, 2023, the NADAC for BUPROPION HCL XL 150 MG TABLET has ranged from a low of $0.0745 (Nov 20, 2024) to a high of $0.1215 (Apr 10, 2024), with a median of $0.1011 per EA.
Are there cheaper alternatives to BUPROPION HCL XL 150 MG TABLET?
Yes. 14 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUPROPION HCL XL 150 MG TABLET, is $0.0779 per EA — about 1% below BUPROPION HCL XL 150 MG TABLET.
Who manufactures BUPROPION HCL XL 150 MG TABLET?
BUPROPION HCL XL 150 MG TABLET (NDC 42806041430) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.