Product Information

BUPROPION HCL XL 150 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.0787 per EA under NDC 16571086212. Its NADAC has been published 99 times since Oct 2, 2024.

FDA first approved this application on Jan 28, 2019. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL XL 150 MG TABLET

bupropion hydrochloride
$0.0787per EA

Strength

150 mg/1

NDC

16571086212

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA211020

FDA Approved

1/28/2019

TE Code

AB3

On Market Since

8/1/2022

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 150 MG TABLET has been published 99 times since Oct 2, 2024, and over the history we have for it it has declined 28.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0787 per EA
All-time high$0.1098 (Oct 16, 2024)
All-time low$0.0745 (Nov 20, 2024)
52-week high$0.1015
52-week low$0.0770
Median price$0.0943
Average price$0.0921
Largest weekly change-30.3% (Nov 20, 2024)
Weeks tracked99
Tracking sinceOct 2, 2024

Price History

1W

+1.2%

1M

+1.1%

3M

-0.3%

6M

+0.2%

1Y

-22.5%

3Y

N/A

5Y

N/A

All

-28.3%

Generic Alternatives

The matcher finds 14 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 150 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 150 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.0787 per EA (NDC 16571086212), effective Aug 19, 2026.

How has the price of BUPROPION HCL XL 150 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 150 MG TABLET has declined 28.3%. It has been tracked across 99 weekly CMS publications since Oct 2, 2024.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 150 MG TABLET?

Since Oct 2, 2024, the NADAC for BUPROPION HCL XL 150 MG TABLET has ranged from a low of $0.0745 (Nov 20, 2024) to a high of $0.1098 (Oct 16, 2024), with a median of $0.0943 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 150 MG TABLET?

Yes. 14 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUPROPION HCL XL 150 MG TABLET, is $0.0779 per EA — about 1% below BUPROPION HCL XL 150 MG TABLET.

Who manufactures BUPROPION HCL XL 150 MG TABLET?

BUPROPION HCL XL 150 MG TABLET (NDC 16571086212) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.