Product Information
METFORMIN HCL ER 500 MG TABLET is a generic product labeled by Epic Pharma LLC, priced at $0.0288 per EA under NDC 42806063201. Its NADAC has been published 263 times since Aug 11, 2021.
FDA first approved this application on Sep 24, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Epic Pharma LLCNDC
42806063201
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA211052FDA Approved
9/24/2018
TE Code
AB1
On Market Since
7/8/2020
Pharmacological Classes
Price Statistics
The NADAC for METFORMIN HCL ER 500 MG TABLET has been published 263 times since Aug 11, 2021, and over the history we have for it it has declined 23.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0288 per EA |
|---|---|
| All-time high | $0.0445 (Nov 16, 2022) |
| All-time low | $0.0238 (Nov 20, 2024) |
| 52-week high | $0.0299 |
| 52-week low | $0.0288 |
| Median price | $0.0314 |
| Average price | $0.0325 |
| Largest weekly change | +29.1% (Feb 22, 2023) |
| Weeks tracked | 263 |
| Tracking since | Aug 11, 2021 |
Generic Alternatives
The matcher finds 10 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 51% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METFORMIN HCL ER 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METFORMIN HCL ER 500 MG TABLET, manufactured by Epic Pharma LLC, is $0.0288 per EA (NDC 42806063201), effective Aug 19, 2026.
How has the price of METFORMIN HCL ER 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for METFORMIN HCL ER 500 MG TABLET has declined 23.2%. It has been tracked across 263 weekly CMS publications since Aug 11, 2021.
What are the highest and lowest recorded NADAC prices for METFORMIN HCL ER 500 MG TABLET?
Since Aug 11, 2021, the NADAC for METFORMIN HCL ER 500 MG TABLET has ranged from a low of $0.0238 (Nov 20, 2024) to a high of $0.0445 (Nov 16, 2022), with a median of $0.0314 per EA.
Are there cheaper alternatives to METFORMIN HCL ER 500 MG TABLET?
Yes. 10 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN HCL 500 MG TABLET, is $0.0140 per EA — about 51% below METFORMIN HCL ER 500 MG TABLET.
Who manufactures METFORMIN HCL ER 500 MG TABLET?
METFORMIN HCL ER 500 MG TABLET (NDC 42806063201) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.