Product Information
METFORMIN HCL 500 MG TABLET is a generic product labeled by Ascend Laboratories, LLC, priced at $0.0145 per EA under NDC 67877093001. Its NADAC has been published 48 times since Nov 5, 2025.
FDA first approved this application on Dec 3, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Ascend Laboratories, LLCNDC
67877093001
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA213320FDA Approved
12/3/2021
TE Code
AB
On Market Since
8/25/2025
Pharmacological Classes
Price Statistics
The NADAC for METFORMIN HCL 500 MG TABLET has been published 48 times since Nov 5, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0145 per EA |
|---|---|
| All-time high | $0.0146 (Dec 10, 2025) |
| All-time low | $0.0139 (Apr 22, 2026) |
| 52-week high | $0.0146 |
| 52-week low | $0.0139 |
| Median price | $0.0140 |
| Average price | $0.0141 |
| Largest weekly change | -3.2% (Dec 17, 2025) |
| Weeks tracked | 48 |
| Tracking since | Nov 5, 2025 |
Generic Alternatives
The matcher finds 10 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Ascend Laboratories, LLC manufacturer profile
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Drug market
METFORMIN HYDROCHLORIDE market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Biguanide class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METFORMIN HCL 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METFORMIN HCL 500 MG TABLET, manufactured by Ascend Laboratories, LLC, is $0.0145 per EA (NDC 67877093001), effective Sep 30, 2026.
How has the price of METFORMIN HCL 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for METFORMIN HCL 500 MG TABLET has held within roughly two percent of its current level. It has been tracked across 48 weekly CMS publications since Nov 5, 2025.
What are the highest and lowest recorded NADAC prices for METFORMIN HCL 500 MG TABLET?
Since Nov 5, 2025, the NADAC for METFORMIN HCL 500 MG TABLET has ranged from a low of $0.0139 (Apr 22, 2026) to a high of $0.0146 (Dec 10, 2025), with a median of $0.0140 per EA.
Are there cheaper alternatives to METFORMIN HCL 500 MG TABLET?
Yes. 10 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN HCL 500 MG TABLET, is $0.0140 per EA — about 4% below METFORMIN HCL 500 MG TABLET.
Who manufactures METFORMIN HCL 500 MG TABLET?
METFORMIN HCL 500 MG TABLET (NDC 67877093001) is labeled by Ascend Laboratories, LLC, and CMS classifies it as a generic product.