Product Information
OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET is a generic product labeled by Rhodes Pharmaceuticals L.P., priced at $0.1195 per EA under NDC 42858010250. Its NADAC has been published 614 times since Nov 19, 2014.
FDA first approved this application on Aug 28, 2014. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 5 mg/1; mg/1
Manufacturer
Rhodes Pharmaceuticals L.P.NDC
42858010250
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ACETAMINOPHEN; OXYCODONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA201278FDA Approved
8/28/2014
TE Code
AA
On Market Since
8/28/2014
Pharmacological Classes
Price Statistics
The NADAC for OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET has been published 614 times since Nov 19, 2014, and over the history we have for it it has declined 33.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1195 per EA |
|---|---|
| All-time high | $0.1802 (Dec 10, 2014) |
| All-time low | $0.0776 (May 20, 2020) |
| 52-week high | $0.1230 |
| 52-week low | $0.1178 |
| Median price | $0.1068 |
| Average price | $0.1130 |
| Largest weekly change | +13.9% (Feb 22, 2023) |
| Weeks tracked | 614 |
| Tracking since | Nov 19, 2014 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 28% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET, manufactured by Rhodes Pharmaceuticals L.P., is $0.1195 per EA (NDC 42858010250), effective Aug 19, 2026.
How has the price of OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET changed over time?
Over the history we have for it, the NADAC for OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET has declined 33.7%. It has been tracked across 614 weekly CMS publications since Nov 19, 2014.
What are the highest and lowest recorded NADAC prices for OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET?
Since Nov 19, 2014, the NADAC for OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET has ranged from a low of $0.0776 (May 20, 2020) to a high of $0.1802 (Dec 10, 2014), with a median of $0.1068 per EA.
Are there cheaper alternatives to OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET, is $0.0864 per EA — about 28% below OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET.
Who manufactures OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET?
OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET (NDC 42858010250) is labeled by Rhodes Pharmaceuticals L.P., and CMS classifies it as a generic product.