Product Information
OXYCODONE-ACETAMINOPHEN 5-325 MG TAB is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $0.1171 per EA under NDC 53746020301. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Nov 27, 2007. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 5 mg/1; mg/1
Manufacturer
Amneal Pharmaceuticals of New York LLCNDC
53746020301
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ACETAMINOPHEN; OXYCODONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040777FDA Approved
11/27/2007
TE Code
AA
On Market Since
11/27/2007
Pharmacological Classes
Price Statistics
The NADAC for OXYCODONE-ACETAMINOPHEN 5-325 MG TAB has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 156.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1171 per EA |
|---|---|
| All-time high | $0.1880 (May 14, 2014) |
| All-time low | $0.0457 (Nov 28, 2013) |
| 52-week high | $0.1228 |
| 52-week low | $0.1171 |
| Median price | $0.1106 |
| Average price | $0.1166 |
| Largest weekly change | +284.0% (Jan 22, 2014) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 26% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Amneal Pharmaceuticals of New York LLC manufacturer profile
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Drug market
Oxycodone and Acetaminophen market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of OXYCODONE-ACETAMINOPHEN 5-325 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for OXYCODONE-ACETAMINOPHEN 5-325 MG TAB, manufactured by Amneal Pharmaceuticals of New York LLC, is $0.1171 per EA (NDC 53746020301), effective Sep 30, 2026.
How has the price of OXYCODONE-ACETAMINOPHEN 5-325 MG TAB changed over time?
Over the history we have for it, the NADAC for OXYCODONE-ACETAMINOPHEN 5-325 MG TAB has risen 156.2%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for OXYCODONE-ACETAMINOPHEN 5-325 MG TAB?
Since Nov 28, 2013, the NADAC for OXYCODONE-ACETAMINOPHEN 5-325 MG TAB has ranged from a low of $0.0457 (Nov 28, 2013) to a high of $0.1880 (May 14, 2014), with a median of $0.1106 per EA.
Are there cheaper alternatives to OXYCODONE-ACETAMINOPHEN 5-325 MG TAB?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, OXYCODONE-ACETAMINOPHEN 5-325 MG TABLET, is $0.0864 per EA — about 26% below OXYCODONE-ACETAMINOPHEN 5-325 MG TAB.
Who manufactures OXYCODONE-ACETAMINOPHEN 5-325 MG TAB?
OXYCODONE-ACETAMINOPHEN 5-325 MG TAB (NDC 53746020301) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.