Product Information
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB is a generic product labeled by Rhodes Pharmaceuticals L.P., priced at $0.2308 per EA under NDC 42858010401. Its NADAC has been published 620 times since Nov 19, 2014.
FDA first approved this application on Aug 28, 2014. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 10 mg/1; mg/1
Manufacturer
Rhodes Pharmaceuticals L.P.NDC
42858010401
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ACETAMINOPHEN; OXYCODONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA201278FDA Approved
8/28/2014
TE Code
AA
On Market Since
8/28/2014
Pharmacological Classes
Price Statistics
The NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TAB has been published 620 times since Nov 19, 2014, and over the history we have for it it has declined 71.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2308 per EA |
|---|---|
| All-time high | $0.7962 (Dec 10, 2014) |
| All-time low | $0.1580 (Sep 22, 2021) |
| 52-week high | $0.2472 |
| 52-week low | $0.2292 |
| Median price | $0.2472 |
| Average price | $0.3301 |
| Largest weekly change | -22.1% (Nov 20, 2024) |
| Weeks tracked | 620 |
| Tracking since | Nov 19, 2014 |
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 22% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Rhodes Pharmaceuticals L.P. manufacturer profile
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Drug market
Oxycodone and Acetaminophen market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of OXYCODONE-ACETAMINOPHEN 10-325 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for OXYCODONE-ACETAMINOPHEN 10-325 MG TAB, manufactured by Rhodes Pharmaceuticals L.P., is $0.2308 per EA (NDC 42858010401), effective Sep 30, 2026.
How has the price of OXYCODONE-ACETAMINOPHEN 10-325 MG TAB changed over time?
Over the history we have for it, the NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TAB has declined 71.0%. It has been tracked across 620 weekly CMS publications since Nov 19, 2014.
What are the highest and lowest recorded NADAC prices for OXYCODONE-ACETAMINOPHEN 10-325 MG TAB?
Since Nov 19, 2014, the NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TAB has ranged from a low of $0.1580 (Sep 22, 2021) to a high of $0.7962 (Dec 10, 2014), with a median of $0.2472 per EA.
Are there cheaper alternatives to OXYCODONE-ACETAMINOPHEN 10-325 MG TAB?
Yes. 12 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET, is $0.1796 per EA — about 22% below OXYCODONE-ACETAMINOPHEN 10-325 MG TAB.
Who manufactures OXYCODONE-ACETAMINOPHEN 10-325 MG TAB?
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB (NDC 42858010401) is labeled by Rhodes Pharmaceuticals L.P., and CMS classifies it as a generic product.