Product Information

HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET is a generic product labeled by Rhodes Pharmaceuticals L.P., priced at $0.1531 per EA under NDC 42858020301. Its NADAC has been published 528 times since May 18, 2016.

HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET

Hydrocodone Bitartrate and Acetaminophen
$0.1531per EA
DEA Schedule CII

Strength

325; 10 mg/1; mg/1

NDC

42858020301

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA202991

On Market Since

4/12/2016

Pharmacological Classes

Opioid Agonist
Opioid Agonists

Price Statistics

The NADAC for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET has been published 528 times since May 18, 2016, and over the history we have for it it has declined 16.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1531 per EA
All-time high$0.1992 (Oct 12, 2016)
All-time low$0.1075 (Nov 20, 2019)
52-week high$0.1613
52-week low$0.1526
Median price$0.1386
Average price$0.1438
Largest weekly change+17.4% (Jun 19, 2024)
Weeks tracked528
Tracking sinceMay 18, 2016

Price History

1W

0.0%

1M

-0.2%

3M

-1.6%

6M

-3.7%

1Y

-4.6%

3Y

+21.7%

5Y

+21.3%

All

-16.4%

Generic Alternatives

The matcher finds 12 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 10 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 12% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET, manufactured by Rhodes Pharmaceuticals L.P., is $0.1531 per EA (NDC 42858020301), effective Jun 24, 2026.

How has the price of HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET changed over time?

Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET has declined 16.4%. It has been tracked across 528 weekly CMS publications since May 18, 2016.

What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?

Since May 18, 2016, the NADAC for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET has ranged from a low of $0.1075 (Nov 20, 2019) to a high of $0.1992 (Oct 12, 2016), with a median of $0.1386 per EA.

Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?

Yes. 12 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET, is $0.1347 per EA — about 12% below HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET.

Who manufactures HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?

HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET (NDC 42858020301) is labeled by Rhodes Pharmaceuticals L.P., and CMS classifies it as a generic product.