Product Information
HYDROCORTISONE 2.5% CREAM is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $0.1252 per GM under NDC 45802000402. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AT.
Strength
25 mg/g
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802000402
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
HYDROCORTISONEApproval Type
Generic (ANDA)
FDA Application
ANDA085025FDA Approved
Before 1982
TE Code
AT
On Market Since
3/31/2006
Pharmacological Classes
Price Statistics
The NADAC for HYDROCORTISONE 2.5% CREAM has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 6.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1252 per GM |
|---|---|
| All-time high | $0.1653 (Nov 15, 2017) |
| All-time low | $0.1032 (Jul 17, 2024) |
| 52-week high | $0.1295 |
| 52-week low | $0.1231 |
| Median price | $0.1328 |
| Average price | $0.1341 |
| Largest weekly change | +38.2% (Aug 21, 2024) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 38% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCORTISONE 2.5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCORTISONE 2.5% CREAM, manufactured by Padagis Israel Pharmaceuticals Ltd, is $0.1252 per GM (NDC 45802000402), effective Aug 19, 2026.
How has the price of HYDROCORTISONE 2.5% CREAM changed over time?
Over the history we have for it, the NADAC for HYDROCORTISONE 2.5% CREAM has declined 6.5%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for HYDROCORTISONE 2.5% CREAM?
Since Nov 28, 2013, the NADAC for HYDROCORTISONE 2.5% CREAM has ranged from a low of $0.1032 (Jul 17, 2024) to a high of $0.1653 (Nov 15, 2017), with a median of $0.1328 per GM.
Are there cheaper alternatives to HYDROCORTISONE 2.5% CREAM?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCORTISONE 2.5% CREAM, is $0.0773 per GM — about 38% below HYDROCORTISONE 2.5% CREAM.
Who manufactures HYDROCORTISONE 2.5% CREAM?
HYDROCORTISONE 2.5% CREAM (NDC 45802000402) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.